Targeted expression of HGF/SF in mouse mammary epithelium leads to metastatic adenosquamous carcinomas through the activation of multiple signal transduction pathways.
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Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergyMET: a critical player in tumorigenesis and therapeutic targetThe clinical and functional significance of c-Met in breast cancer: a reviewDistinct gene-expression profiles characterize mammary tumors developed in transgenic mice expressing constitutively active and C-terminally truncated variants of STAT5.MET and MYC cooperate in mammary tumorigenesis.In vitro and in vivo effects of suppressor of cytokine signalling 7 knockdown in breast cancer: the influence on cellular response to hepatocyte growth factor.Expression of hepatocyte growth factor and its receptor c-Met in human pituitary adenomasThe Met oncogene and basal-like breast cancer: another culprit to watch out for?Mouse models of breast cancer metastasis.TLR4 ligand/H₂O₂ enhances TGF-β1 signaling to induce metastatic potential of non-invasive breast cancer cells by activating non-Smad pathways.In vivo direct molecular imaging of early tumorigenesis and malignant progression induced by transgenic expression of GFP-Met.Short-Form Ron Promotes Spontaneous Breast Cancer Metastasis through Interaction with Phosphoinositide 3-Kinase.Epidermal growth factor receptor plays a significant role in hepatocyte growth factor mediated biological responses in mammary epithelial cellsHGFL supports mammary tumorigenesis by enhancing tumor cell intrinsic survival and influencing macrophage and T-cell responses.Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling.Somatic mutation and functional polymorphism of a novel regulatory element in the HGF gene promoter causes its aberrant expression in human breast cancer.3,3'-diindolylmethane rapidly and selectively inhibits hepatocyte growth factor/c-Met signaling in breast cancer cellsKnockdown of RON receptor kinase delays but does not prevent tumor progression while enhancing HGF/MET signaling in pancreatic cancer cell lines.Met induces diverse mammary carcinomas in mice and is associated with human basal breast cancer.Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancer.Selection criteria for c-Met-targeted therapies: emerging evidence for biomarkers.The role of growth factors in intestinal regeneration and repair in necrotizing enterocolitis.Gene expression profiling of HGF/Met activation in neonatal mouse heart.An Orthotopic Mouse Model of Spontaneous Breast Cancer Metastasis.Fucoidan Suppresses Hypoxia-Induced Lymphangiogenesis and Lymphatic Metastasis in Mouse Hepatocarcinoma.LoVo colon cancer cells resistant to oxaliplatin overexpress c-MET and VEGFR-1 and respond to VEGF with dephosphorylation of c-MET.Study of critical role of c-Met and its inhibitor SU11274 in colorectal carcinoma.Intracellular IL-37b interacts with Smad3 to suppress multiple signaling pathways and the metastatic phenotype of tumor cells.Targeting the hsp70 gene delays mammary tumor initiation and inhibits tumor cell metastasis.MACC1 is related to colorectal cancer initiation and early-stage invasive growth.Identifying differentially expressed genes in cancer patients using a non-parameter Ising model.A novel activating function of c-Src and Stat3 on HGF transcription in mammary carcinoma cells.Rho/ROCK-dependent pseudopodial protrusion and cellular blebbing are regulated by p38 MAPK in tumour cells exhibiting autocrine c-Met activation.
P2860
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P2860
Targeted expression of HGF/SF in mouse mammary epithelium leads to metastatic adenosquamous carcinomas through the activation of multiple signal transduction pathways.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Targeted expression of HGF/SF ...... signal transduction pathways.
@en
Targeted expression of HGF/SF ...... signal transduction pathways.
@nl
type
label
Targeted expression of HGF/SF ...... signal transduction pathways.
@en
Targeted expression of HGF/SF ...... signal transduction pathways.
@nl
prefLabel
Targeted expression of HGF/SF ...... signal transduction pathways.
@en
Targeted expression of HGF/SF ...... signal transduction pathways.
@nl
P2860
P356
P1433
P1476
Targeted expression of HGF/SF ...... e signal transduction pathways
@en
P2093
Brian Bierie
Marta I Gallego
P2860
P2888
P304
P356
10.1038/SJ.ONC.1207063
P407
P577
2003-11-01T00:00:00Z