The isoleucyl-tRNA synthetase mutation V588F conferring mupirocin resistance in glycopeptide-intermediate Staphylococcus aureus is not associated with a significant fitness burden.

The isoleucyl-tRNA synthetase mutation V588F conferring mupirocin resistance in glycopeptide-intermediate Staphylococcus aureus is not associated with a significant fitness burden.

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http://www.wikidata.org/entity/Q44681057
Evolution of MRSA during hospital transmission and intercontinental spreadPlasmidic qnrA3 enhances Escherichia coli fitness in absence of antibiotic exposure.Impact of combined low-level mupirocin and genotypic chlorhexidine resistance on persistent methicillin-resistant Staphylococcus aureus carriage after decolonization therapy: a case-control study.In vivo transfer of high-level mupirocin resistance from Staphylococcus epidermidis to methicillin-resistant Staphylococcus aureus associated with failure of mupirocin prophylaxis.Prospects for aminoacyl-tRNA synthetase inhibitors as new antimicrobial agents.Aminoacyl-tRNA synthetases: essential and still promising targets for new anti-infective agents.Current and Emerging Topical Antibacterials and Antiseptics: Agents, Action, and Resistance Patterns.Analysis of mupirocin resistance and fitness in Staphylococcus aureus by molecular genetic and structural modeling techniques.Targeting Multiple Aminoacyl-tRNA Synthetases Overcomes the Resistance Liabilities Associated with Antibacterial Inhibitors Acting on a Single Such Enzyme.Acquisition of high-level mupirocin resistance and its fitness cost among methicillin-resistant Staphylococcus aureus strains with low-level mupirocin resistance.Genetic basis of resistance to fusidic acid in staphylococci.In vitro and in vivo evaluations of the activities of lauric acid monoester formulations against Staphylococcus aureus.Genome sequence of a recently emerged, highly transmissible, multi-antibiotic- and antiseptic-resistant variant of methicillin-resistant Staphylococcus aureus, sequence type 239 (TW).Molecular genetic and structural modeling studies of Staphylococcus aureus RNA polymerase and the fitness of rifampin resistance genotypes in relation to clinical prevalence.Activity of and development of resistance to corallopyronin A, an inhibitor of RNA polymerase.Analysis of mutational resistance to trimethoprim in Staphylococcus aureus by genetic and structural modelling techniques.Epistasis analysis uncovers hidden antibiotic resistance-associated fitness costs hampering the evolution of MRSA
P2860

The isoleucyl-tRNA synthetase mutation V588F conferring mupirocin resistance in glycopeptide-intermediate Staphylococcus aureus is not associated with a significant fitness burden.

Item
http://www.wikidata.org/entity/Q44681057
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The isoleucyl-tRNA synthetase ...... a significant fitness burden.
@en
The isoleucyl-tRNA synthetase ...... a significant fitness burden.
@nl
type
label
The isoleucyl-tRNA synthetase ...... a significant fitness burden.
@en
The isoleucyl-tRNA synthetase ...... a significant fitness burden.
@nl
prefLabel
The isoleucyl-tRNA synthetase ...... a significant fitness burden.
@en
The isoleucyl-tRNA synthetase ...... a significant fitness burden.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
The isoleucyl-tRNA synthetase ...... h a significant fitness burden
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698