uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV.
about
Endosomes generate localized Rho-ROCK-MLC2-based contractile signals via Endo180 to promote adhesion disassemblyThe collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review)The urokinase receptor (uPAR) and the uPAR-associated protein (uPARAP/Endo180): membrane proteins engaged in matrix turnover during tissue remodelingEndo180 binds to the C-terminal region of type I collagenM2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway.Up-regulation of uPARAP/Endo180 during culture activation of rat hepatic stellate cells and its presence in hepatic stellate cell lines from different speciesA role for fibrillar collagen deposition and the collagen internalization receptor endo180 in glioma invasion.Endocytosis of collagen by hepatic stellate cells regulates extracellular matrix dynamics.Fibrocytes are not an essential source of type I collagen during lung fibrosis.SPRY1 promotes the degradation of uPAR and inhibits uPAR-mediated cell adhesion and proliferationDifferential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasisThe non-phagocytic route of collagen uptake: a distinct degradation pathway.Provisional Matrix Deposition in Hemostasis and Venous Insufficiency: Tissue Preconditioning for Nonhealing Venous Ulcers.A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uparap/ENDO180Regulation of reactionary dentin formation by odontoblasts in response to polymicrobial invasion of dentin matrix.Mannose receptor 2 attenuates renal fibrosisRole of urokinase plasminogen activator receptor-associated protein in mouse lungComplementary roles of intracellular and pericellular collagen degradation pathways in vivo.Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy.Antiprotease therapy in cancer: hot or not?Differential regulation of extracellular tissue inhibitor of metalloproteinases-3 levels by cell membrane-bound and shed low density lipoprotein receptor-related protein 1.Live-cell imaging demonstrates extracellular matrix degradation in association with active cathepsin B in caveolae of endothelial cells during tube formation.3D/4D functional imaging of tumor-associated proteolysis: impact of microenvironment.MT2-MMP-dependent release of collagen IV NC1 domains regulates submandibular gland branching morphogenesis.Complex determinants in specific members of the mannose receptor family govern collagen endocytosisDownregulation of uPARAP mediates cytoskeletal rearrangements and decreases invasion and migration properties in glioma cells.Investigating the Origins of Toxic Response in TiO₂ Nanoparticle-Treated CellsMembrane type-1 matrix metalloproteinase activity is regulated by the endocytic collagen receptor Endo180.The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers.uPARAP expression during murine lung development.Uptake of denatured collagen into hepatic stellate cells: evidence for the involvement of urokinase plasminogen activator receptor-associated protein/Endo180.On how mammary gland reprogramming metalloproteinases couple form with function.New and paradoxical roles of matrix metalloproteinases in the tumor microenvironment.Expression of Endo180 is spatially and temporally regulated during wound healing.Structural model for the mannose receptor family uncovered by electron microscopy of Endo180 and the mannose receptor.Tumor-Associated Macrophages Derived from Circulating Inflammatory Monocytes Degrade Collagen through Cellular Uptake.Serine proteases, inhibitors and receptors in renal fibrosis.Phagocytosis of Collagen Fibrils by Fibroblasts In Vivo Is Independent of the uPARAP/Endo180 Receptor.Design, characterization and cellular uptake studies of fluorescence-labeled prototypic cathepsin inhibitors.Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation.
P2860
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P2860
uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV.
@en
uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV.
@nl
type
label
uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV.
@en
uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV.
@nl
prefLabel
uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV.
@en
uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV.
@nl
P2093
P50
P1476
uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV
@en
P2093
Lars Kjøller
Maria Høyer-Hansen
P304
P356
10.1016/J.YEXCR.2003.10.008
P407
P577
2004-02-01T00:00:00Z