Rapid hepatic metabolism of 7-ketocholesterol by 11beta-hydroxysteroid dehydrogenase type 1: species-specific differences between the rat, human, and hamster enzyme.
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Appropriate function of 11beta-hydroxysteroid dehydrogenase type 1 in the endoplasmic reticulum lumen is dependent on its N-terminal region sharing similar topological determinants with 50-kDa esteraseCharacterization of novel StAR (steroidogenic acute regulatory protein) mutations causing non-classic lipoid adrenal hyperplasiaDHEA induces 11 -HSD2 by acting on CCAAT/enhancer-binding proteinsHexose-6-phosphate dehydrogenase modulates 11beta-hydroxysteroid dehydrogenase type 1-dependent metabolism of 7-keto- and 7beta-hydroxy-neurosteroidsOn the formation of 7-ketocholesterol from 7-dehydrocholesterol in patients with CTX and SLO.Cutaneous glucocorticosteroidogenesis: securing local homeostasis and the skin integrity.11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice.Reduction of hepatic glucocorticoid receptor and hexose-6-phosphate dehydrogenase expression ameliorates diet-induced obesity and insulin resistance in mice.Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1.Oxysterols in biological systems: sources, metabolism and pathophysiological relevance.11β-hydroxysteroid dehydrogenases and the brain: from zero to hero, a decade of progress.Hexose-6-phosphate dehydrogenase contributes to skeletal muscle homeostasis independent of 11β-hydroxysteroid dehydrogenase type 1.The multifaceted mineralocorticoid receptorStructural characterization of human cholesterol 7α-hydroxylase11β-Hydroxysteroid dehydrogenase type 1 contributes to the balance between 7-keto- and 7-hydroxy-oxysterols in vivo.Cytochromes p450 and skin cancer: role of local endocrine pathways.Impaired oxidoreduction by 11β-hydroxysteroid dehydrogenase 1 results in the accumulation of 7-oxolithocholic acid.Therapeutic manipulation of glucocorticoid metabolism in cardiovascular diseaseSide effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis.Oxysterols in biological systems: the gastrointestinal tract, liver, vascular wall and central nervous system.11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action.Human microsomal carbonyl reducing enzymes in the metabolism of xenobiotics: well-known and promising members of the SDR superfamily.Glucocorticoid metabolism in rheumatoid arthritis.Hexose-6-phosphate dehydrogenase determines the reaction direction of 11beta-hydroxysteroid dehydrogenase type 1 as an oxoreductase.Interactions between dehydroepiandrosterone and glucocorticoid metabolism in pig kidney: nuclear and microsomal 11beta-hydroxysteroid dehydrogenases.The Influence of an Obesogenic Diet on Oxysterol Metabolism in C57BL/6J Mice.Hepatic reduction of the secondary bile acid 7-oxolithocholic acid is mediated by 11β-hydroxysteroid dehydrogenase 1.Fructose promotes the differentiation of 3T3-L1 adipocytes and accelerates lipid metabolism.Evolution of 11beta-hydroxysteroid dehydrogenase-type 1 and 11beta-hydroxysteroid dehydrogenase-type 3.11β-Hydroxysteroid dehydrogenase type 1 contributes to the regulation of 7-oxysterol levels in the arterial wall through the inter-conversion of 7-ketocholesterol and 7β-hydroxycholesterol.Diazepane-acetamide derivatives as selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors.Lipidomics reveals accumulation of the oxidized cholesterol in erythrocytes of heart failure patients.Synergistic interaction of fatty acids and oxysterols impairs mitochondrial function and limits liver adaptation during nafld progression.Dehydroepiandrosterone metabolites and their interactions in humans.
P2860
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P2860
Rapid hepatic metabolism of 7-ketocholesterol by 11beta-hydroxysteroid dehydrogenase type 1: species-specific differences between the rat, human, and hamster enzyme.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Rapid hepatic metabolism of 7- ...... at, human, and hamster enzyme.
@en
Rapid hepatic metabolism of 7- ...... at, human, and hamster enzyme.
@nl
type
label
Rapid hepatic metabolism of 7- ...... at, human, and hamster enzyme.
@en
Rapid hepatic metabolism of 7- ...... at, human, and hamster enzyme.
@nl
prefLabel
Rapid hepatic metabolism of 7- ...... at, human, and hamster enzyme.
@en
Rapid hepatic metabolism of 7- ...... at, human, and hamster enzyme.
@nl
P2093
P2860
P356
P1476
Rapid hepatic metabolism of 7- ...... at, human, and hamster enzyme.
@en
P2093
Alex Odermatt
Bernhard Dick
Marcel Zürcher
Roberto A S Schweizer
Zoltan Balazs
P2860
P304
18415-18424
P356
10.1074/JBC.M313615200
P407
P577
2004-02-18T00:00:00Z