about
Epimutational profile of hematologic malignancies as attractive target for new epigenetic therapiesPediatric AML: From Biology to Clinical ManagementLeukemogenic rearrangements at the mixed lineage leukemia gene (MLL)-multiple rather than a single mechanismConnections between TET proteins and aberrant DNA modification in cancerLeukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding.The super elongation complex (SEC) and MLL in development and disease.The prognostic and functional role of microRNAs in acute myeloid leukemiaTET2 mutations improve the new European LeukemiaNet risk classification of acute myeloid leukemia: a Cancer and Leukemia Group B study.Targeted Cancer Therapy: Vital Oncogenes and a New Molecular Genetic Paradigm for Cancer Initiation Progression and TreatmentRole of HOXA9 in leukemia: dysregulation, cofactors and essential targetsIn vitro transformation of primary human CD34+ cells by AML fusion oncogenes: early gene expression profiling reveals possible drug target in AMLOverexpression of the catalytically impaired Taspase1 T234V or Taspase1 D233A variants does not have a dominant negative effect in T(4;11) leukemia cellsRegistered report: Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukemiaThe behaviour of 5-hydroxymethylcytosine in bisulfite sequencingCircos: an information aesthetic for comparative genomicsDisordered epigenetic regulation in MLL-related leukemia.The Superiority of Allogeneic Hematopoietic Stem Cell Transplantation Over Chemotherapy Alone in the Treatment of Acute Myeloid Leukemia Patients with Mixed Lineage Leukemia (MLL) Rearrangements.Quantitative comparison of microarray experiments with published leukemia related gene expression signatures.Genetic tests to evaluate prognosis and predict therapeutic response in acute myeloid leukemia.Chromatin modifications as therapeutic targets in MLL-rearranged leukemia.A novel spliced fusion of MLL with CT45A2 in a pediatric biphenotypic acute leukemia.Epigenetics: an emerging player in gastric cancerMixed lineage leukemia-septin 5 fusion transcript in de novo adult acute myeloid leukemia with t(11;22)(q23;q11.2): A case reportHypermethylation and down-regulation of DLEU2 in paediatric acute myeloid leukaemia independent of embedded tumour suppressor miR-15a/16-1.Homozygous inv(11)(q21q23) and MLL gene rearrangement in two patients with myeloid neoplasmsPromoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting.Chromatin proteins and modifications as drug targets.MLL-rearranged B lymphoblastic leukemias selectively express the immunoregulatory carbohydrate-binding protein galectin-1.Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study.Genome wide analysis of acute myeloid leukemia reveal leukemia specific methylome and subtype specific hypomethylation of repeats.DNA methylation analysis of bone marrow cells at diagnosis of acute lymphoblastic leukemia and at remission.Prognostic significance of 11q23 aberrations in adult acute myeloid leukemia and the role of allogeneic stem cell transplantation.Soluble plasma HLA peptidome as a potential source for cancer biomarkersDevelopment of a multi-step leukemogenesis model of MLL-rearranged leukemia using humanized miceDevelopment of five dual-color, double-fusion fluorescence in situ hybridization assays for the detection of common MLL translocation partnersThe MLL recombinome of acute leukemias in 2013.Development of a high-throughput screening-compatible assay for the discovery of inhibitors of the AF4-AF9 interaction using AlphaScreen technologyDown-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferationRequirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways.
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
New insights to the MLL recombinome of acute leukemias.
@en
New insights to the MLL recombinome of acute leukemias.
@nl
type
label
New insights to the MLL recombinome of acute leukemias.
@en
New insights to the MLL recombinome of acute leukemias.
@nl
prefLabel
New insights to the MLL recombinome of acute leukemias.
@en
New insights to the MLL recombinome of acute leukemias.
@nl
P2093
P2860
P50
P356
P1433
P1476
New insights to the MLL recombinome of acute leukemias.
@en
P2093
A Renneville
A Teigler-Schlegel
B V Balgobind
B W Schäfer
C N Alonso
D Ilencikova
P2860
P2888
P304
P356
10.1038/LEU.2009.33
P50
P577
2009-03-05T00:00:00Z
P5875
P6179
1020913485