Effects of chronic glucocorticoid administration on insulin-degrading enzyme and amyloid-beta peptide in the aged macaque. - Wikidata - awgldk - TriplyDB

Effects of chronic glucocorticoid administration on insulin-degrading enzyme and amyloid-beta peptide in the aged macaque.

Effects of chronic glucocorticoid administration on insulin-degrading enzyme and amyloid-beta peptide in the aged macaque.

http://www.wikidata.org/entity/Q45307020

about

Unified theory of Alzheimer's disease (UTAD): implications for prevention and curative therapy Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription Stress and dementia: the role of the hypothalamicpituitary-adrenal axis.Extracellular biotransformation of beta-endorphin in rat striatum and cerebrospinal fluid.Adverse stress, hippocampal networks, and Alzheimer's disease.3xTgAD mice exhibit altered behavior and elevated Aβ after chronic mild social stress Effects of stress and stress hormones on amyloid-beta protein and plaque deposition.Brain neurotoxic amyloid-beta peptides: their potential role in the pathophysiology of depression and as molecular therapeutic targets.Interactions between age, stress and insulin on cognition: implications for Alzheimer's disease Age-associated evolution of plasmatic amyloid in mouse lemur primates: relationship with intracellular amyloid deposition.Time-dependent changes in gene expression induced by secreted amyloid precursor protein-alpha in the rat hippocampus Corticosteroids, but not NSAIDs, are associated with less Alzheimer neuropathology.Immune function and HPA axis activity in free-ranging rhesus macaques.Aging and physical mobility in group-housed Old World monkeys Lower CSF amyloid beta peptides and higher F2-isoprostanes in cognitively intact elderly individuals with major depressive disorder Plasma beta amyloid level and depression in older adults.Short-term modern life-like stress exacerbates Aβ-pathology and synapse loss in 3xTg-AD mice Mifepristone alters amyloid precursor protein processing to preclude amyloid beta and also reduces tau pathology.A new glucocorticoid hypothesis of brain aging: implications for Alzheimer's disease Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus Positive and negative early life experiences differentially modulate long term survival and amyloid protein levels in a mouse model of Alzheimer's disease.11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action.Zinc signaling through glucocorticoid and glutamate signaling in stressful circumstances.Chronic high levels of the RCAN1-1 protein may promote neurodegeneration and Alzheimer disease.Dominance of the hypothalamus-pituitary-adrenal axis over the renin-angiotensin-aldosterone system is a risk factor for decreased insulin secretion.Insight into glutamate excitotoxicity from synaptic zinc homeostasis Chronic exogenous corticosterone administration generates an insulin-resistant brain state in rats.The role of declining adaptive homeostasis in ageing.Humoral immune responses to peptides derived from the beta-amyloid peptide C-terminal sequence.Cerebrospinal fluid levels of soluble amyloid precursor protein and β-amyloid 42 in patients with multiple sclerosis, neuromyelitis optica and clinically isolated syndrome.Long-term cortisol measures predict Alzheimer disease risk.Targeting glucocorticoid receptors prevents the effects of early life stress on amyloid pathology and cognitive performance in APP/PS1 mice.The unique value of primate models in translational research Vulnerability and resilience to Alzheimer's disease: early life conditions modulate neuropathology and determine cognitive reserve Brain Physiology and Pathophysiology in Mental Stress

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P2860

Effects of chronic glucocorticoid administration on insulin-degrading enzyme and amyloid-beta peptide in the aged macaque.

http://www.wikidata.org/entity/Q45307020

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2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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Effects of chronic glucocortic ...... a peptide in the aged macaque.

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Effects of chronic glucocortic ...... a peptide in the aged macaque.

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Effects of chronic glucocortic ...... a peptide in the aged macaque.

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Effects of chronic glucocortic ...... a peptide in the aged macaque.

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Effects of chronic glucocortic ...... a peptide in the aged macaque.

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P1433

Journal of Neuropathology & Experimental Neurology

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Effects of chronic glucocortic ...... ta peptide in the aged macaque

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P2093

David G Cook

http://www.w3.org/2001/XMLSchema#string

Elaine R Peskind

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J Jacob Kulstad

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Pamela J McMillan

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Pankaj D Mehta

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Pattie S Green

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Suzanne Craft

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Wesley Farris

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P2860

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

Insulin degradation: progress and potential

Glucocorticoids and insulin resistance: old hormones, new targets.

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo

Clearing amyloid through the blood-brain barrier.

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139-146

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10.1093/JNEN/64.2.139

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2

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64

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James B Leverenz

Charles W. Wilkinson

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2005-02-01T00:00:00Z

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290213001

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15751228

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