about
The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cellsRequirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/TxkEtk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation.Direct inhibition of Bruton's tyrosine kinase by IBtk, a Btk-binding proteinInteraction of Bruton's tyrosine kinase and protein kinase Ctheta in platelets. Cross-talk between tyrosine and serine/threonine kinasesA new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondriaA conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cellsThe role of tyrosine kinase Etk/Bmx in EGF-induced apoptosis of MDA-MB-468 breast cancer cellsIdentification and characterization of a molecule, BAM11, that associates with the pleckstrin homology domain of mouse BtkSHIP family inositol phosphatases interact with and negatively regulate the Tec tyrosine kinase.In situ detection of activated Bruton's tyrosine kinase in the Ig signaling complex by phosphopeptide-specific monoclonal antibodies.Btk regulates B cell receptor-mediated antigen processing and presentation by controlling actin cytoskeleton dynamics in B cells.Future therapeutic targets in rheumatoid arthritis?B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals.Phosphoinositide 3-kinase and Bruton's tyrosine kinase regulate overlapping sets of genes in B lymphocytesReduced diabetes in btk-deficient nonobese diabetic mice and restoration of diabetes with provision of an anti-insulin IgH chain transgeneThe effects of the Epstein-Barr virus latent membrane protein 2A on B cell function.Posttranscriptional regulation of Bruton's tyrosine kinase expression in antigen receptor-stimulated splenic B cells.Regulation of oxidative stress-induced calcium release by phosphatidylinositol 3-kinase and Bruton's tyrosine kinase in B cells.Regulation of protein kinase CbetaI by two protein-tyrosine kinases, Btk and SykRole of Bruton's tyrosine kinase inhibitors in HIV-1-infected cellsA sensitized genetic system for the analysis of murine B lymphocyte signal transduction pathways dependent on Bruton's tyrosine kinase.Genetic Interaction between Lyn, Ets1, and Btk in the Control of Antibody Levels.Detection of Selection Signatures on the X Chromosome in Three Sheep Breeds.Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk.Tec family kinases modulate thresholds for thymocyte development and selection.B cell antigen receptor specificity and surface density together determine B-1 versus B-2 cell development.B1 B lymphocytes play a critical role in host protection against lymphatic filarial parasites.Analysis of the Effects of the Bruton's tyrosine kinase (Btk) Inhibitor Ibrutinib on Monocyte Fcγ Receptor (FcγR) Function.Expression and function of Tec, Itk, and Btk in lymphocytes: evidence for a unique role for TecMechanisms underlying in vivo polysaccharide-specific immunoglobulin responses to intact extracellular bacteria.Tec family kinases in inflammation and disease.Tyrosine kinase inhibitors as potential drugs for B-cell lymphoid malignancies and autoimmune disorders.Microbial modulation of host immunity with the small molecule phosphorylcholine.BCR signaling in chronic lymphocytic leukemia and related inhibitors currently in clinical studies.Ibrutinib and novel BTK inhibitors in clinical development.Relevance of lymphocyte subsets to B cell-targeted therapy in systemic lupus erythematosus.Gene expression profiles and signaling mechanisms in α2B-adrenoceptor-evoked proliferation of vascular smooth muscle cells.Amplification of IL-21 signalling pathway through Bruton's tyrosine kinase in human B cell activation.Cell-specific association and shuttling of IkappaBalpha provides a mechanism for nuclear NF-kappaB in B lymphocytes.
P2860
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P2860
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Btk function in B cell development and response.
@en
Btk function in B cell development and response.
@nl
type
label
Btk function in B cell development and response.
@en
Btk function in B cell development and response.
@nl
prefLabel
Btk function in B cell development and response.
@en
Btk function in B cell development and response.
@nl
P2093
P356
P1476
Btk function in B cell development and response.
@en
P2093
P304
P356
10.1006/SMIM.1998.0123
P577
1998-08-01T00:00:00Z