Requirement for an interaction of XRCC4 with DNA ligase IV for wild-type V(D)J recombination and DNA double-strand break repair in vivo.
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In vitro and in vivo interactions of DNA ligase IV with a subunit of the condensin complexBiochemical characterization of metnase's endonuclease activity and its role in NHEJ repairDNA binding of Xrcc4 protein is associated with V(D)J recombination but not with stimulation of DNA ligase IV activitySUMO modification of human XRCC4 regulates its localization and function in DNA double-strand break repair.Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IVOncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switchingCrystal structure of the Xrcc4 DNA repair protein and implications for end joiningAntisense-mediated decrease in DNA ligase III expression results in reduced mitochondrial DNA integrityBRCT domains: easy as one, two, threeStructural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4Genetic variants of NHEJ DNA ligase IV can affect the risk of developing multiple myeloma, a tumour characterised by aberrant class switch recombinationThe biochemistry and biological significance of nonhomologous DNA end joining: an essential repair process in multicellular eukaryotesDNA ligase IV and XRCC4 form a stable mixed tetramer that functions synergistically with other repair factors in a cell-free end-joining systemRole of non-homologous end joining in V(D)J recombinationAncient and recent adaptive evolution of primate non-homologous end joining genesEarly embryonic lethality due to targeted inactivation of DNA ligase IIIIdentification of proteins in the hamster DNA end-binding complex.Extreme growth failure is a common presentation of ligase IV deficiency.Both V(D)J recombination and radioresistance require DNA-PK kinase activity, though minimal levels suffice for V(D)J recombination.Regulation of the DNA Damage Response to DSBs by Post-Translational Modifications.DNA Ligase IV regulates XRCC4 nuclear localization.Cytotoxicity associated with artemis overexpression after lentiviral vector-mediated gene transfer.A novel missense RAG-1 mutation results in T-B-NK+ SCID in Athabascan-speaking Dine Indians from the Canadian Northwest Territories.XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair.Dual modes of interaction between XRCC4 and polynucleotide kinase/phosphatase: implications for nonhomologous end joining.Analysis of DNA ligase IV mutations found in LIG4 syndrome patients: the impact of two linked polymorphisms.DNA ligases as therapeutic targetsA single amino acid substitution in DNA-PKcs explains the novel phenotype of the CHO mutant, XR-C2.XLF regulates filament architecture of the XRCC4·ligase IV complex.Characterization of the human artemis promoter by heterologous gene expression in vitro and in vivo.Successful bone marrow transplantation in a patient with DNA ligase IV deficiency and bone marrow failureOrganization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repairGenome-wide screens for sensitivity to ionizing radiation identify the fission yeast nonhomologous end joining factor Xrc4.The DNA-dependent protein kinase: the director at the end.Artemis sheds new light on V(D)J recombination.Loss of DNA ligase IV prevents recognition of DNA by double-strand break repair proteins XRCC4 and XLFDNA double-strand break repair and development.DNA repair in murine embryonic stem cells and differentiated cellsE1B 55k-independent dissociation of the DNA ligase IV/XRCC4 complex by E4 34k during adenovirus infectionRole of the yeast DNA repair protein Nej1 in end processing during the repair of DNA double strand breaks by non-homologous end joining
P2860
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P2860
Requirement for an interaction of XRCC4 with DNA ligase IV for wild-type V(D)J recombination and DNA double-strand break repair in vivo.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Requirement for an interaction of XRCC4 with DNA ligase IV for wild-type V
@nl
Requirement for an interaction ...... e-strand break repair in vivo.
@en
type
label
Requirement for an interaction of XRCC4 with DNA ligase IV for wild-type V
@nl
Requirement for an interaction ...... e-strand break repair in vivo.
@en
prefLabel
Requirement for an interaction of XRCC4 with DNA ligase IV for wild-type V
@nl
Requirement for an interaction ...... e-strand break repair in vivo.
@en
P2093
P2860
P356
P1476
Requirement for an interaction ...... e-strand break repair in vivo.
@en
P2093
P2860
P304
24708-24714
P356
10.1074/JBC.273.38.24708
P407
P577
1998-09-01T00:00:00Z