Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma.
about
MHC class I antigen processing and presenting machinery: organization, function, and defects in tumor cellsAntigenic peptide trimming by ER aminopeptidases--insights from structural studiesStructural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1Identification of E2F1 as an important transcription factor for the regulation of tapasin expression.Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation.Endoplasmic reticulum aminopeptidase-1 alleles associated with increased risk of ankylosing spondylitis reduce HLA-B27 mediated presentation of multiple antigens.A role for naturally occurring alleles of endoplasmic reticulum aminopeptidases in tumor immunity and cancer pre-disposition.Differences in genetic variation in antigen-processing machinery components and association with cervical carcinoma risk in two Indonesian populations.Role of endoplasmic reticulum aminopeptidases in health and disease: from infection to cancer.Genetic association with ERAP1 in psoriasis is confined to disease onset after puberty and not dependent on HLA-C*06.p53 increases MHC class I expression by upregulating the endoplasmic reticulum aminopeptidase ERAP1Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.Progress in spondylarthritis. Progress in studies of the genetics of ankylosing spondylitis.Cervical Carcinogenesis and Immune Response Gene Polymorphisms: A Review.Single Nucleotide Polymorphisms of the ERAP1 Gene and Risk of NSCLC: A Comparison of Genetically Distant Populations, Chinese and Caucasian.Post-proteasomal and proteasome-independent generation of MHC class I ligands.Treatment failure in patients with HPV 16-induced vulvar intraepithelial neoplasia: understanding different clinical responses to immunotherapy.Positioning of aminopeptidase inhibitors in next generation cancer therapy.Endoplasmic reticulum aminopeptidase 1 function and its pathogenic role in regulating innate and adaptive immunity in cancer and major histocompatibility complex class I-associated autoimmune diseases.Genetic associations and functional characterization of M1 aminopeptidases and immune-mediated diseases.ERAP1 in the pathogenesis of ankylosing spondylitis.Nucleic acid tool enzymes-aided signal amplification strategy for biochemical analysis: status and challenges.Antigen processing and immune regulation in the response to tumours.Differences between disease-associated endoplasmic reticulum aminopeptidase 1 (ERAP1) isoforms in cellular expression, interactions with tumour necrosis factor receptor 1 (TNF-R1) and regulation by cytokines.Secretion of endoplasmic reticulum aminopeptidase 1 is involved in the activation of macrophages induced by lipopolysaccharide and interferon-gammaImmune evasion mechanisms of human papillomavirus: An update.Proper genomic profiling of (BRCA1-mutated) basal-like breast carcinomas requires prior removal of tumor infiltrating lymphocytes.The Role of Conformational Dynamics in Antigen Trimming by Intracellular Aminopeptidases.Sculpting MHC class II-restricted self and non-self peptidome by the class I Ag-processing machinery and its impact on Th-cell responses.A polymorphism in ERAP1 is associated with susceptibility to ankylosing spondylitis in a Turkish population.Molecular backgrounds of ERAP1 downregulation in cervical carcinoma.The role of polymorphic ERAP1 in autoinflammatory diseaseNext Generation Cancer Vaccines-Make It Personal!
P2860
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P2860
Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Single nucleotide polymorphism ...... outcome in cervical carcinoma.
@en
Single nucleotide polymorphism ...... outcome in cervical carcinoma.
@nl
type
label
Single nucleotide polymorphism ...... outcome in cervical carcinoma.
@en
Single nucleotide polymorphism ...... outcome in cervical carcinoma.
@nl
prefLabel
Single nucleotide polymorphism ...... outcome in cervical carcinoma.
@en
Single nucleotide polymorphism ...... outcome in cervical carcinoma.
@nl
P2093
P2860
P50
P356
P1476
Single nucleotide polymorphism ...... outcome in cervical carcinoma
@en
P2093
Gert Jan Fleuren
Hae-Won Uh
Willem E Corver
P2860
P304
P356
10.1002/GCC.20648
P577
2009-05-01T00:00:00Z