Cytochrome P450 3A4-catalyzed testosterone 6beta-hydroxylation stereochemistry, kinetic deuterium isotope effects, and rate-limiting steps.
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Hydrocarbon hydroxylation by cytochrome P450 enzymesKinetic deuterium isotope effects in cytochrome P450 oxidation reactionsUntargeted analysis of mass spectrometry data for elucidation of metabolites and function of enzymes.Kinetic analysis of lauric acid hydroxylation by human cytochrome P450 4A11Mechanism of the third oxidative step in the conversion of androgens to estrogens by cytochrome P450 19A1 steroid aromatase.Cytochrome P450 7A1 cholesterol 7alpha-hydroxylation: individual reaction steps in the catalytic cycle and rate-limiting ferric iron reductionA malleable catalyst dominates the metabolism of drugs.Spectral modification and catalytic inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2A6, and 2A13 by four chemopreventive organoselenium compoundsAb initio dynamics of the cytochrome P450 hydroxylation reactionRapid and quantitative measurement of metabolic stability without chromatography or mass spectrometryThe diverse chemistry of cytochrome P450 17A1 (P450c17, CYP17A1).Current Approaches for Investigating and Predicting Cytochrome P450 3A4-Ligand InteractionsOxidation of dihydrotestosterone by human cytochromes P450 19A1 and 3A4.Minor activities and transition state properties of the human steroid hydroxylases cytochromes P450c17 and P450c21, from reactions observed with deuterium-labeled substrates.mRNA distribution and heterologous expression of orphan cytochrome P450 20A1Allylic oxidations catalyzed by dirhodium caprolactamate via aqueous tert-butyl hydroperoxide: the role of the tert-butylperoxy radical.Theoretical characterization of substrate access/exit channels in the human cytochrome P450 3A4 enzyme: involvement of phenylalanine residues in the gating mechanism.Cooperative properties of cytochromes P450.Rapid kinetic methods to dissect steroidogenic cytochrome P450 reaction mechanisms.Chromatographic assays of drug oxidation by human cytochrome P450 3A4Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivativesHuman germline hedgehog pathway mutations predispose to fatty liver.Male-specific induction of CYP3A2 in rats by zolmitriptan.Kinetics and thermodynamics of ligand binding by cytochrome P450 3A4.Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins.Digging Deeper into CYP3A Testosterone Metabolism: Kinetic, Regioselectivity, and Stereoselectivity Differences between CYP3A4/5 and CYP3A7.Kinetic Deuterium Isotope Effects in Cytochrome P450 Reactions.Origin of the Regioselective Fatty-Acid Hydroxylation versus Decarboxylation by a Cytochrome P450 Peroxygenase: What Drives the Reaction to Biofuel Production?Selected scientific topics of the 11th International Isotope Symposium on the Synthesis and Applications of Isotopes and Isotopically Labeled Compounds.Electron transport pathway for a Streptomyces cytochrome P450: cytochrome P450 105D5-catalyzed fatty acid hydroxylation in Streptomyces coelicolor A3(2).Cytochrome P450 Monooxygenase-Catalyzed Ring Opening of the Bicyclic Amine, Nortropine: An Experimental and DFT Computational StudyPharmacokinetics, metabolism and safety of deuterated L-DOPA (SD-1077)/carbidopa compared to L-DOPA/carbidopa following single oral dose administration in healthy subjects
P2860
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P2860
Cytochrome P450 3A4-catalyzed testosterone 6beta-hydroxylation stereochemistry, kinetic deuterium isotope effects, and rate-limiting steps.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Cytochrome P450 3A4-catalyzed ...... ects, and rate-limiting steps.
@en
Cytochrome P450 3A4-catalyzed ...... ects, and rate-limiting steps.
@nl
type
label
Cytochrome P450 3A4-catalyzed ...... ects, and rate-limiting steps.
@en
Cytochrome P450 3A4-catalyzed ...... ects, and rate-limiting steps.
@nl
prefLabel
Cytochrome P450 3A4-catalyzed ...... ects, and rate-limiting steps.
@en
Cytochrome P450 3A4-catalyzed ...... ects, and rate-limiting steps.
@nl
P2860
P356
P1476
Cytochrome P450 3A4-catalyzed ...... ects, and rate-limiting steps.
@en
P2093
F Peter Guengerich
Joel A Krauser
P2860
P304
19496-19506
P356
10.1074/JBC.M501854200
P407
P577
2005-03-15T00:00:00Z