Excitotoxic injury to mitochondria isolated from cultured neurons.
about
Loss of OPA1 disturbs cellular calcium homeostasis and sensitizes for excitotoxicity.GM1 and NGF modulate Ca2+ homeostasis and GAP43 mRNA expression in cultured dorsal root ganglion neurons with excitotoxicity induced by glutamate.Neuregulin-1β prevents Ca(2+) overloading and apoptosis through PI3K/Akt activation in cultured dorsal root ganglion neurons with excitotoxicity induced by glutamate.Mitochondrial calcium uptake capacity as a therapeutic target in the R6/2 mouse model of Huntington's disease.Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis.Causes and consequences of methamphetamine and MDMA toxicity.Intravenous (-)-epicatechin reduces myocardial ischemic injury by protecting mitochondrial function.Computational Analysis of AMPK-Mediated Neuroprotection Suggests Acute Excitotoxic Bioenergetics and Glucose Dynamics Are Regulated by a Minimal Set of Critical ReactionsThiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier.Calcium-induced precipitate formation in brain mitochondria: composition, calcium capacity, and retentionCa2+/calmodulin-dependent protein kinase IV links group I metabotropic glutamate receptors to fragile X mental retardation protein in cingulate cortex.Mitochondrial Ca2+ sequestration and precipitation revisited.Models of calcium dynamics in cerebellar granule cells.The metabolic response to excitotoxicity - lessons from single-cell imaging.Calpain activation and Na+/Ca2+ exchanger degradation occur downstream of calcium deregulation in hippocampal neurons exposed to excitotoxic glutamate6-Hydroxydopamine activates the mitochondrial apoptosis pathway through p38 MAPK-mediated, p53-independent activation of Bax and PUMA.Mutant huntingtin expression induces mitochondrial calcium handling defects in clonal striatal cells: functional consequences.Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death.Role of cyclophilin D-dependent mitochondrial permeability transition in glutamate-induced calcium deregulation and excitotoxic neuronal death.Glutamate mobilizes [Zn2+] through Ca2+ -dependent reactive oxygen species accumulation.HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism.Inhibitory effect of homocysteine on rat neural stem cell growth in vitro is associated with reduced protein levels and enzymatic activities of aconitase and respiratory complex III.NMDA receptor-mediated excitotoxic neuronal apoptosis in vitro and in vivo occurs in an ER stress and PUMA independent manner.Reduced calcium-dependent mitochondrial damage underlies the reduced vulnerability of excitotoxicity-tolerant hippocampal neurons.Ca2+-dependent generation of mitochondrial reactive oxygen species serves as a signal for poly(ADP-ribose) polymerase-1 activation during glutamate excitotoxicity.Calcium-dependent spontaneously reversible remodeling of brain mitochondria.
P2860
Q30532888-461BB97D-8BED-4C3F-A783-4ACCE0C91FD0Q33306050-078350A8-EBB8-4DCF-8194-C88424A571DCQ33931785-5198397D-DCBA-459D-B072-5DF6CDB04E24Q34046887-7A045359-4E95-4578-B4DE-E991E27B41F5Q34575828-DBEA1DAE-7451-414A-945F-17B6239E9003Q35594881-BEC4B9BF-DD1A-4161-B302-F39FFA22A212Q35862403-E444F2F1-7187-4C33-8BC6-2B0EFB91A726Q35913395-B0AC6811-337D-45D3-BD87-55CDEB6B635EQ36747796-03D2C416-DB24-4F74-95CF-94DCD597D97CQ36935277-EB8C5D08-C9D1-4C58-B19A-4DB94D5A6F3EQ37254039-8B3632EB-2860-408E-9A18-62CBA297D6F9Q37775697-624F1AB7-2914-4B2F-9483-4F5DDF414784Q37797956-57C2BE1B-C920-46E4-8F8C-1AAAE6AA3EB7Q38254907-9227CB05-7AE0-4075-B585-A7D32C0C3FFEQ39339387-DC462FD1-A320-4EAA-997F-92CD7A17EB72Q40053611-8AB8670B-4FD6-4C91-A7A1-1BB486A607D6Q40231756-4F0A39CB-7F4C-482A-8EBF-21191068CF43Q41946111-FADFF4FA-92CA-4CC3-A453-E72D6AF356C7Q42019992-903677E8-04D8-4C72-9196-6C0142B4F61FQ42924122-F3D13BD4-6AC5-4898-8500-397478C12247Q45298206-8FE8E172-6242-4AB7-8697-81634BF6EB14Q46450895-BD6D4DF6-D48B-4B0B-B2D6-B07BAD504149Q46844313-4BB2BB26-5B0D-428F-BBBD-FA080BC91721Q46884165-66FC1B59-08A9-4F86-9C4A-50022EE332A6Q46942358-95083CD7-78FA-499B-8B2B-47E052812B6DQ48390266-F17CA389-EC64-4EEF-82EF-69CCDCE8386F
P2860
Excitotoxic injury to mitochondria isolated from cultured neurons.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Excitotoxic injury to mitochondria isolated from cultured neurons.
@en
Excitotoxic injury to mitochondria isolated from cultured neurons.
@nl
type
label
Excitotoxic injury to mitochondria isolated from cultured neurons.
@en
Excitotoxic injury to mitochondria isolated from cultured neurons.
@nl
prefLabel
Excitotoxic injury to mitochondria isolated from cultured neurons.
@en
Excitotoxic injury to mitochondria isolated from cultured neurons.
@nl
P2860
P50
P356
P1476
Excitotoxic injury to mitochondria isolated from cultured neurons
@en
P2093
Sandra E Wiley
Yulia E Kushnareva
P2860
P304
28894-28902
P356
10.1074/JBC.M503090200
P407
P577
2005-06-02T00:00:00Z