Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells.

Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells.

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http://www.wikidata.org/entity/Q46549512
On the Quest of Cellular Functions of PEA-15 and the Therapeutic OpportunitiesPhosphoprotein enriched in astrocytes 15 kDa (PEA-15) reprograms growth factor signaling by inhibiting threonine phosphorylation of fibroblast receptor substrate 2alpha.Obesity and microbiota: an example of an intricate relationship.Discovery of small peptide antagonists of PED/PEA15-D4α interaction from simplified combinatorial libraries.Phosphoprotein enriched in astrocytes (PEA)-15: a potential therapeutic target in multiple disease states.PED/PEA-15 inhibits hydrogen peroxide-induced apoptosis in Ins-1E pancreatic beta-cells via PLD-1Adenoviral gene transfer of PLD1-D4 enhances insulin sensitivity in mice by disrupting phospholipase D1 interaction with PED/PEA-15.Substantial conformational change mediated by charge-triad residues of the death effector domain in protein-protein interactionsPhospholipase D: enzymology, functionality, and chemical modulationPEA-15 potentiates H-Ras-mediated epithelial cell transformation through phospholipase DPeroxisome proliferator-activated receptor-γ activation enhances insulin-stimulated glucose disposal by reducing ped/pea-15 gene expression in skeletal muscle cells: evidence for involvement of activator protein-1Targetting PED/PEA-15 for diabetes treatment.NMR backbone dynamics studies of human PED/PEA-15 outline protein functional sites.
P2860

Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells.

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http://www.wikidata.org/entity/Q46549512
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2008 nî lūn-bûn
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Targeting of PED/PEA-15 molecu ...... vity in skeletal muscle cells.
@en
Targeting of PED/PEA-15 molecu ...... vity in skeletal muscle cells.
@nl
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label
Targeting of PED/PEA-15 molecu ...... vity in skeletal muscle cells.
@en
Targeting of PED/PEA-15 molecu ...... vity in skeletal muscle cells.
@nl
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Targeting of PED/PEA-15 molecu ...... vity in skeletal muscle cells.
@en
Targeting of PED/PEA-15 molecu ...... vity in skeletal muscle cells.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P356
P1433
P1476
Targeting of PED/PEA-15 molecu ...... ivity in skeletal muscle cells
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921