Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin. - Wikidata - awgldk - TriplyDB

Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin.

Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin.

http://www.wikidata.org/entity/Q46755710

about

Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation.Increased expression of cholesterol 24S-hydroxylase results in disruption of glial glutamate transporter EAAT2 association with lipid rafts: a potential role in Alzheimer's disease Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's disease Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1 Amyloidosis in Retinal Neurodegenerative Diseases Protein prenylation and synaptic plasticity: implications for Alzheimer's disease Cholesterol balance in prion diseases and Alzheimer's disease Axonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cells Roles and regulation of neutral sphingomyelinase-2 in cellular and pathological processes The Impact of Vitamin E and Other Fat-Soluble Vitamins on Alzheimer´s Disease Ceramides in Alzheimer's Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and Aβ Accumulation Interleukin-1 beta impairs brain derived neurotrophic factor-induced signal transduction ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice.Clues to neuro-degeneration in Niemann-Pick type C disease from global gene expression profiling Cholesterol-modifying strategies for Alzheimer's disease.New Alzheimer amyloid beta responsive genes identified in human neuroblastoma cells by hierarchical clustering.Increase in sphingolipid catabolic enzyme activity during aging.Inherent anti-amyloidogenic activity of human immunoglobulin gamma heavy chains Cross-talk of membrane lipids and Alzheimer-related proteins.Oxidative Stress, Synaptic Dysfunction, and Alzheimer's Disease.The role of exon shuffling in shaping protein-protein interaction networks.Endoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol trafficking Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer's disease.Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer's disease.Lipid rafts participate in aberrant degradative autophagic-lysosomal pathway of amyloid-beta peptide in Alzheimer's disease Molecular insights into amyloid regulation by membrane cholesterol and sphingolipids: common mechanisms in neurodegenerative diseases Amyloid precursor protein (APP) mediated regulation of ganglioside homeostasis linking Alzheimer's disease pathology with ganglioside metabolism.Cerebrospinal fluid sphingolipids, β-amyloid, and tau in adults at risk for Alzheimer's disease.Immunogenic properties of amyloid beta oligomers.Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer's disease.Ceramide and Related-Sphingolipid Levels Are Not Altered in Disease-Associated Brain Regions of APP and APP/PS1 Mouse Models of Alzheimer's Disease: Relationship with the Lack of Neurodegeneration?Core-shell upconversion nanoparticle - semiconductor heterostructures for photodynamic therapy.Plasmalogen synthesis is regulated via alkyl-dihydroxyacetonephosphate-synthase by amyloid precursor protein processing and is affected in Alzheimer's disease.The intracellular threonine of amyloid precursor protein that is essential for docking of Pin1 is dispensable for developmental function.Regulation of phosphatidic Acid metabolism by sphingolipids in the central nervous system Pathological and physiological functions of presenilins.Elevation in sphingomyelin synthase activity is associated with increases in amyloid-beta peptide generation.Intracellular APP Domain Regulates Serine-Palmitoyl-CoA Transferase Expression and Is Affected in Alzheimer's Disease.Alterations of the sphingolipid pathway in Alzheimer's disease: new biomarkers and treatment targets?Upregulation of PGC-1α expression by Alzheimer's disease-associated pathway: presenilin 1/amyloid precursor protein (APP)/intracellular domain of APP

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Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin.

http://www.wikidata.org/entity/Q46755710

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin.

@en

Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin.

@nl

type

label

Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin.

@en

Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin.

@nl

prefLabel

Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin.

@en

Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin.

@nl

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Nature Cell Biology

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Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin.

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P2093

Andreas J Pätzold

http://www.w3.org/2001/XMLSchema#string

Eva G Zinser

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Heike S Grimm

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Jakob A Tschäpe

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Jie Shen

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Marcus O W Grimm

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Riikka Halonen

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Ulrike Müller

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1118-1123

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scholarly article

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10.1038/NCB1313

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11

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7

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Tobias Hartmann

Bart De Strooper

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2005-11-01T00:00:00Z

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232781795

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