BCR-ABL regulates phosphatidylinositol 3-kinase-p110gamma transcription and activation and is required for proliferation and drug resistance.
about
The PI3K pathway as drug target in human cancerTargeting p110gamma in gastrointestinal cancers: attack on multiple frontsRole of calcium-dependent protein kinases in chronic myeloid leukemia: combined effects of PKC and BCR-ABL signaling on cellular alterations during leukemia developmentStructure-Based Design of an Organoruthenium Phosphatidyl-inositol-3-kinase Inhibitor Reveals a Switch Governing Lipid Kinase Potency and SelectivityThe p110δ structure: mechanisms for selectivity and potency of new PI(3)K inhibitorsTargeting the phosphoinositide 3-kinase pathway in hematologic malignanciesPhosphatidylinositol 3-kinase: the oncoprotein.Comprehensive predictions of target proteins based on protein-chemical interaction using virtual screening and experimental verifications.Oncogenic transformation induced by the p110beta, -gamma, and -delta isoforms of class I phosphoinositide 3-kinasePI3Kδ is essential for tumor clearance mediated by cytotoxic T lymphocytes.Novel PI3Kγ mutation in a 44-year-old man with chronic infections and chronic pelvic painThe p110δ subunit of PI3K regulates bone marrow-derived eosinophil trafficking and airway eosinophilia in allergen-challenged mice.Class I PI3K in oncogenic cellular transformation.Take your PIK: phosphatidylinositol 3-kinase inhibitors race through the clinic and toward cancer therapy.Novel inhibitors of the PI3K family.Inhibitors of phosphatidylinositol-3-kinase in cancer therapyMultiple roles for the p85α isoform in the regulation and function of PI3K signalling and receptor trafficking.Targeting the PI3K pathway for cancer therapy.Co-operating STAT5 and AKT signaling pathways in chronic myeloid leukemia and mastocytosis: possible new targets of therapy.PI3K/AKT signaling pathway and cancer: an updated review.Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway.Oncogenic signaling of class I PI3K isoforms.Insulin-like growth factor-1 activates different catalytic subunits p110 of PI3K in a cell-type-dependent manner to induce lipogenesis-dependent epithelial-mesenchymal transition through the regulation of ADAM10 and ADAM17.Role of a novel benzoxazine derivative in the chemosensitization of colon cancer.Inhibition of Ras-mediated signaling pathways in CML stem cells.Studies on the expression patterns of class I PI3K catalytic subunits and its prognostic significance in colorectal cancer.
P2860
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P2860
BCR-ABL regulates phosphatidylinositol 3-kinase-p110gamma transcription and activation and is required for proliferation and drug resistance.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
BCR-ABL regulates phosphatidyl ...... iferation and drug resistance.
@en
BCR-ABL regulates phosphatidyl ...... iferation and drug resistance.
@nl
type
label
BCR-ABL regulates phosphatidyl ...... iferation and drug resistance.
@en
BCR-ABL regulates phosphatidyl ...... iferation and drug resistance.
@nl
prefLabel
BCR-ABL regulates phosphatidyl ...... iferation and drug resistance.
@en
BCR-ABL regulates phosphatidyl ...... iferation and drug resistance.
@nl
P2860
P356
P1476
BCR-ABL regulates phosphatidyl ...... liferation and drug resistance
@en
P2093
Fionnuala B Hickey
Thomas G Cotter
P2860
P304
P356
10.1074/JBC.M511173200
P407
P577
2005-11-16T00:00:00Z