Destruction box-dependent degradation of aurora B is mediated by the anaphase-promoting complex/cyclosome and Cdh1.
about
The function of APC/CCdh1 in cell cycle and beyondAPC/C(Cdh1) targets brain-specific kinase 2 (BRSK2) for degradation via the ubiquitin-proteasome pathwayPharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damageAurora B interacts with NIR-p53, leading to p53 phosphorylation in its DNA-binding domain and subsequent functional suppressionThe adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memoryFunctional importance of the anaphase-promoting complex-Cdh1-mediated degradation of TMAP/CKAP2 in regulation of spindle function and cytokinesis.Insights into APC/C: from cellular function to diseases and therapeuticsUbiquitin-Mediated Degradation of Aurora KinasesFunctions of Aurora kinase C in meiosis and cancerFunctional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesisCasein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis.APC(CDH1) targets MgcRacGAP for destruction in the late M phaseTCR affinity associated with functional differences between dominant and subdominant SIV epitope-specific CD8+ T cells in Mamu-A*01+ rhesus monkeysAPC/C and retinoblastoma interaction: cross-talk of retinoblastoma protein with the ubiquitin proteasome pathwayUbiquitin and SUMO systems in the regulation of mitotic checkpointsHSP90 inhibition enhances antimitotic drug-induced mitotic arrest and cell death in preclinical models of non-small cell lung cancerRegulation of glia number in Drosophila by Rap/Fzr, an activator of the anaphase-promoting complex, and Loco, an RGS proteinDictyostelium Aurora kinase has properties of both Aurora A and Aurora B kinases.MLL5 maintains genomic integrity by regulating the stability of the chromosomal passenger complex through a functional interaction with BorealinSpatiotemporal organization of Aurora-B by APC/CCdh1 after mitosis coordinates cell spreading through FHOD1.Sequestration of CDH1 by MAD2L2 prevents premature APC/C activation prior to anaphase onset.The Aurora B kinase in Trypanosoma brucei undergoes post-translational modifications and is targeted to various subcellular locations through binding to TbCPC1.Cytokinetic abscission is an acute G1 event.Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancerAPC(cdh1) mediates degradation of the oncogenic Rho-GEF Ect2 after mitosis.The aurora kinases in cell cycle and leukemiaThe transcription factor YY1 is a novel substrate for Aurora B kinase at G2/M transition of the cell cycleCKAP2 is a spindle-associated protein degraded by APC/C-Cdh1 during mitotic exit.Cell cycle-dependent expression of centrosomal ninein-like protein in human cells is regulated by the anaphase-promoting complex.Understanding cytokinesis failure.APC/C(Cdh1) controls CtIP stability during the cell cycle and in response to DNA damage.RABL6A, a novel RAB-like protein, controls centrosome amplification and chromosome instability in primary fibroblasts.Insights into phosphorylation-dependent mechanisms regulating USP1 protein stability during the cell cycle.Emerging regulatory mechanisms in ubiquitin-dependent cell cycle control.Maternally recruited Aurora C kinase is more stable than Aurora B to support mouse oocyte maturation and early developmentBaculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cellsFBXW7 is involved in Aurora B degradation.Regulation of the Aurora B chromosome passenger protein complex during oocyte maturation in Xenopus laevis.Overview of major classes of plant-derived anticancer drugsAurora B prevents delayed DNA replication and premature mitotic exit by repressing p21(Cip1).
P2860
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P2860
Destruction box-dependent degradation of aurora B is mediated by the anaphase-promoting complex/cyclosome and Cdh1.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Destruction box-dependent degr ...... ng complex/cyclosome and Cdh1.
@en
Destruction box-dependent degr ...... ng complex/cyclosome and Cdh1.
@nl
type
label
Destruction box-dependent degr ...... ng complex/cyclosome and Cdh1.
@en
Destruction box-dependent degr ...... ng complex/cyclosome and Cdh1.
@nl
prefLabel
Destruction box-dependent degr ...... ng complex/cyclosome and Cdh1.
@en
Destruction box-dependent degr ...... ng complex/cyclosome and Cdh1.
@nl
P1433
P1476
Destruction box-dependent degr ...... ng complex/cyclosome and Cdh1.
@en
P2093
Guowei Fang
Scott Stewart
P304
P356
10.1158/0008-5472.CAN-05-1500
P407
P577
2005-10-01T00:00:00Z