Activated p53 suppresses the histone methyltransferase EZH2 gene. - Wikidata - awgldk - TriplyDB

Activated p53 suppresses the histone methyltransferase EZH2 gene.

Activated p53 suppresses the histone methyltransferase EZH2 gene.

http://www.wikidata.org/entity/Q47314793

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Functional characterization of EZH2β reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expression The transcription factor p53: not a repressor, solely an activator The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells Development of New Molecular EZH2 on Lung Cancer Invasion and Metastasis EZH2 in Bladder Cancer, a Promising Therapeutic Target Expression of polycomb group protein EZH2 in nevi and melanoma.EZH2: not EZHY (easy) to deal.Focal adhesion kinase depletion reduces human hepatocellular carcinoma growth by repressing enhancer of zeste homolog 2.Cancer angiogenesis induced by Kaposi sarcoma-associated herpesvirus is mediated by EZH2.Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes.Number of polyploid giant cancer cells and expression of EZH2 are associated with VM formation and tumor grade in human ovarian tumor.p53-mediated hematopoietic stem and progenitor cell competition.An epistatic relationship between the viral protein kinase UL97 and the UL133-UL138 latency locus during the human cytomegalovirus lytic cycle.Functional and therapeutic significance of EZH2 in urological cancers The molecular balancing act of p16(INK4a) in cancer and aging.The prognostic role of EZH2 expression in rectal cancer patients treated with neoadjuvant chemoradiotherapy Clinical and biological relevance of enhancer of zeste homolog 2 in triple-negative breast cancer.The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion Epigenetics of prostate cancer: beyond DNA methylation c-Rel regulates Ezh2 expression in activated lymphocytes and malignant lymphoid cells Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblasts Pharmacologic down-regulation of EZH2 suppresses bladder cancer in vitro and in vivo.The transcriptional repressor ZBTB4 regulates EZH2 through a MicroRNA-ZBTB4-specificity protein signaling axis Concurrent activation of acetylation and tri-methylation of H3K27 in a subset of hepatocellular carcinoma with aggressive behavior Transcriptomes and shRNA suppressors in a TP53 allele-specific model of early-onset colon cancer in African Americans.Histone modifiers in cancer: friends or foes?Evidence for alteration of EZH2, BMI1, and KDM6A and epigenetic reprogramming in human papillomavirus type 16 E6/E7-expressing keratinocytes Sulforaphane suppresses polycomb group protein level via a proteasome-dependent mechanism in skin cancer cells.MK3 modulation affects BMI1-dependent and independent cell cycle check-points.Myc enforces overexpression of EZH2 in early prostatic neoplasia via transcriptional and post-transcriptional mechanisms Connections between epigenetic gene silencing and human disease.EZH2 silencing with RNAi enhances irradiation-induced inhibition of human lung cancer growth in vitro and in vivo.Inhibition of autophagy and tumor growth in colon cancer by miR-502.MicroRNA-98 and microRNA-214 post-transcriptionally regulate enhancer of zeste homolog 2 and inhibit migration and invasion in human esophageal squamous cell carcinoma Retinoblastoma-binding Protein 4-regulated Classical Nuclear Transport Is Involved in Cellular Senescence.Inhibition of EZH2 suppresses self-renewal and induces radiation sensitivity in atypical rhabdoid teratoid tumor cells.Mutant p53 induces EZH2 expression and promotes epithelial-mesenchymal transition by disrupting p68-Drosha complex assembly and attenuating miR-26a processing Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation.High EZH2 Protein Expression Is Associated with Poor Overall Survival in Patients with Luminal A Breast Cancer

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P2860

Activated p53 suppresses the histone methyltransferase EZH2 gene.

http://www.wikidata.org/entity/Q47314793

description

2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年學術文章

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2004年學術文章

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name

Activated p53 suppresses the histone methyltransferase EZH2 gene.

@en

Activated p53 suppresses the histone methyltransferase EZH2 gene.

@nl

type

label

Activated p53 suppresses the histone methyltransferase EZH2 gene.

@en

Activated p53 suppresses the histone methyltransferase EZH2 gene.

@nl

prefLabel

Activated p53 suppresses the histone methyltransferase EZH2 gene.

@en

Activated p53 suppresses the histone methyltransferase EZH2 gene.

@nl

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Activated p53 suppresses the histone methyltransferase EZH2 gene.

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Igor Shats

http://www.w3.org/2001/XMLSchema#string

Michael Milyavsky

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Naomi Goldfinger

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Varda Rotter

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Xiaohu Tang

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34

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