Apolipoprotein E receptors mediate neurite outgrowth through activation of p44/42 mitogen-activated protein kinase in primary neurons.
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Reelin and apoE actions on signal transduction, synaptic function and memory formationApolipoprotein E receptor 2 interactions with the N-methyl-D-aspartate receptorLDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin.Valproic acid induces astrocyte-dependent neurite outgrowth from cultured rat primary cortical neuron via modulation of tPA/PAI-1 activityExtensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's diseaseLDL receptor-related protein-1: a regulator of inflammation in atherosclerosis, cancer, and injury to the nervous systemEnrichment of cholesterol in microdissected Alzheimer's disease senile plaques as assessed by mass spectrometry.Macrophage LRP-1 controls plaque cellularity by regulating efferocytosis and Akt activation.Low-density lipoprotein receptor-related protein-1 mediates endocytic clearance of tissue inhibitor of metalloproteinases-1 and promotes its cytokine-like activitiesAPOE and neuroenergetics: an emerging paradigm in Alzheimer's disease.LDL receptor-related protein 1 regulates the abundance of diverse cell-signaling proteins in the plasma membrane proteome.ApoE receptor 2 regulates synapse and dendritic spine formationApolipoprotein E: structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases.Metallothionein and a peptide modeled after metallothionein, EmtinB, induce neuronal differentiation and survival through binding to receptors of the low-density lipoprotein receptor family.Metallothionein promotes regenerative axonal sprouting of dorsal root ganglion neurons after physical axotomyRegulation of cytokine expression by Schwann cells in response to α2-macroglobulin binding to LRP1.Alpha2-macroglobulin is a mediator of retinal ganglion cell death in glaucoma.Abeta42 neurotoxicity in primary co-cultures: effect of apoE isoform and Abeta conformation.LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein.Transthyretin provides trophic support via megalin by promoting neurite outgrowth and neuroprotection in cerebral ischemiaNeuronal nicotinic acetylcholine receptor-cholesterol crosstalk in Alzheimer's disease.Apolipoprotein E as a β-amyloid-independent factor in Alzheimer's disease.Innate immune responses to HIV infection in the central nervous system.The dark sides of amyloid in Alzheimer's disease pathogenesis.Urokinase-type plasminogen activator (uPA) and its receptor (uPAR) promote neurorepair in the ischemic brain.ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion.Role of LRP1 in the pathogenesis of Alzheimer's disease: evidence from clinical and preclinical studies.Molecular dissection of the human alpha2-macroglobulin subunit reveals domains with antagonistic activities in cell signaling.The functional role of the second NPXY motif of the LRP1 beta-chain in tissue-type plasminogen activator-mediated activation of N-methyl-D-aspartate receptors.Low-density lipoprotein receptor-related protein 1 is a novel modulator of radial glia stem cell proliferation, survival, and differentiation.Ligand binding to LRP1 transactivates Trk receptors by a Src family kinase-dependent pathway.The activities of LDL Receptor-related Protein-1 (LRP1) compartmentalize into distinct plasma membrane microdomains.APP independent and dependent effects on neurite outgrowth are modulated by the receptor associated protein (RAP).Fyn kinase regulates the association between amyloid precursor protein and Dab1 by promoting their localization to detergent-resistant membranes.Apolipoprotein E decreases tau kinases and phospho-tau levels in primary neurons.Sp1 is up-regulated in cellular and transgenic models of Huntington disease, and its reduction is neuroprotective.tPA regulates neurite outgrowth by phosphorylation of LRP5/6 in neural progenitor cells.Roles of apolipoprotein E4 (ApoE4) in the pathogenesis of Alzheimer's disease: lessons from ApoE mouse models.Nerve growth factor-mediated regulation of low density lipoprotein receptor-related protein promoter activation.Multiple pathways of apolipoprotein E signaling in primary neurons.
P2860
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P2860
Apolipoprotein E receptors mediate neurite outgrowth through activation of p44/42 mitogen-activated protein kinase in primary neurons.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
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@yue
2004年學術文章
@zh-hant
name
Apolipoprotein E receptors med ...... ein kinase in primary neurons.
@en
Apolipoprotein E receptors med ...... ein kinase in primary neurons.
@nl
type
label
Apolipoprotein E receptors med ...... ein kinase in primary neurons.
@en
Apolipoprotein E receptors med ...... ein kinase in primary neurons.
@nl
prefLabel
Apolipoprotein E receptors med ...... ein kinase in primary neurons.
@en
Apolipoprotein E receptors med ...... ein kinase in primary neurons.
@nl
P2860
P356
P1476
Apolipoprotein E receptors med ...... ein kinase in primary neurons.
@en
P2093
G William Rebeck
Zhihua Qiu
P2860
P304
34948-34956
P356
10.1074/JBC.M401055200
P407
P577
2004-05-28T00:00:00Z