The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type I.
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A role for Alström syndrome protein, alms1, in kidney ciliogenesis and cellular quiescenceExpression of PKD1 and PKD2 transcripts and proteins in human embryo and during normal kidney developmentSevere pancreas hypoplasia and multicystic renal dysplasia in two human fetuses carrying novel HNF1beta/MODY5 mutationsPolycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutationCiliary polycystin-2 is a mechanosensitive calcium channel involved in nitric oxide signaling cascadesRetinoic acid-dependent activation of the polycystic kidney disease-1 (PKD1) promoterThe structure of a PKD domain from polycystin-1: implications for polycystic kidney disease.Renal cystic disease in tuberous sclerosis: role of the polycystic kidney disease 1 geneA spectrum of mutations in the second gene for autosomal dominant polycystic kidney disease (PKD2)The activin receptor-like kinase 1 gene: genomic structure and mutations in hereditary hemorrhagic telangiectasia type 2Role of calcium in polycystic kidney disease: From signaling to pathologyVascular complications in autosomal dominant polycystic kidney diseaseA polycystin-centric view of cyst formation and disease: the polycystins revisitedPolycystin-1: a master regulator of intersecting cystic pathwaysNovel role of ouabain as a cystogenic factor in autosomal dominant polycystic kidney diseasePolycystin-1 cleavage and the regulation of transcriptional pathwaysPolycystic kidney disease - where gene dosage countsModelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroidsPkd1 and Pkd2 are required for normal placental developmentSystems biology of polycystic kidney disease: a critical reviewIn vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2Mutations of the human polycystic kidney disease 2 (PKD2) geneBilineal disease and trans-heterozygotes in autosomal dominant polycystic kidney disease.Cardiac defects and renal failure in mice with targeted mutations in Pkd2Pkd2 haploinsufficiency alters intracellular calcium regulation in vascular smooth muscle cellsA tumor necrosis factor-alpha-mediated pathway promoting autosomal dominant polycystic kidney diseaseTAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complexA genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formationA non-synonymous mutation in the canine Pkd1 gene is associated with autosomal dominant polycystic kidney disease in Bull Terriers.Polycystin-1 is required for stereocilia structure but not for mechanotransduction in inner ear hair cells.Pkd1 transgenic mice: adult model of polycystic kidney disease with extrarenal and renal phenotypes.Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion.Loss of oriented cell division does not initiate cyst formationPolycystin signaling is required for directed endothelial cell migration and lymphatic developmentThe cytoplasmic C-terminal fragment of polycystin-1 regulates a Ca2+-permeable cation channel.Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models.Low-dose rapamycin (sirolimus) effects in autosomal dominant polycystic kidney disease: an open-label randomized controlled pilot study.
P2860
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P2860
The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type I.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh-hant
name
The molecular basis of focal c ...... ycystic kidney disease type I.
@en
The molecular basis of focal c ...... ycystic kidney disease type I.
@nl
type
label
The molecular basis of focal c ...... ycystic kidney disease type I.
@en
The molecular basis of focal c ...... ycystic kidney disease type I.
@nl
prefLabel
The molecular basis of focal c ...... ycystic kidney disease type I.
@en
The molecular basis of focal c ...... ycystic kidney disease type I.
@nl
P2093
P1433
P1476
The molecular basis of focal c ...... ycystic kidney disease type I.
@en
P2093
P304
P356
10.1016/S0092-8674(00)81793-6
P407
P577
1996-12-01T00:00:00Z