Molecular profiling identifies prognostic subgroups of pediatric glioblastoma and shows increased YB-1 expression in tumors. - Wikidata - awgldk - TriplyDB

Molecular profiling identifies prognostic subgroups of pediatric glioblastoma and shows increased YB-1 expression in tumors.

Molecular profiling identifies prognostic subgroups of pediatric glioblastoma and shows increased YB-1 expression in tumors.

http://www.wikidata.org/entity/Q48221611

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Mechanistic evaluation of the novel HSP90 inhibitor NVP-AUY922 in adult and pediatric glioblastoma Molecular Biology in Pediatric High-Grade Glioma: Impact on Prognosis and Treatment Epigenetic dysregulation: a novel pathway of oncogenesis in pediatric brain tumors Surmounting chemoresistance by targeting the Y-box binding protein-1 The therapeutic potential of targeting the PI3K pathway in pediatric brain tumors Forfeited hepatogenesis program and increased embryonic stem cell traits in young hepatocellular carcinoma (HCC) comparing to elderly HCC Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development RSK in tumorigenesis: connections to steroid signaling.Contribution of tumor heterogeneity in a new animal model of CNS tumors.The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma Pediatric high-grade glioma: biologically and clinically in need of new thinking Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability.Genome-wide profiling using single-nucleotide polymorphism arrays identifies novel chromosomal imbalances in pediatric glioblastomas Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas.Akt activation is a common event in pediatric malignant gliomas and a potential adverse prognostic marker: a report from the Children's Oncology Group.Genome-wide methylation profiling identifies an essential role of reactive oxygen species in pediatric glioblastoma multiforme and validates a methylome specific for H3 histone family 3A with absence of G-CIMP/isocitrate dehydrogenase 1 mutation.Extracellular vesicles as prospective carriers of oncogenic protein signatures in adult and paediatric brain tumours.Gene expression profiling of gliomas: merging genomic and histopathological classification for personalised therapy.Impact of tumor location and pathological discordance on survival of children with midline high-grade gliomas treated on Children's Cancer Group high-grade glioma study CCG-945.Histologically proven, low-grade brainstem gliomas in children: 30-year experience with long-term follow-up at Mayo Clinic.Management of high-grade gliomas in the pediatric patient: Past, present, and future.Concise review: bullseye: targeting cancer stem cells to improve the treatment of gliomas by repurposing disulfiram.Pediatric high-grade glioma: identification of poly(ADP-ribose) polymerase as a potential therapeutic target.Deregulation of ion channel and transporter encoding genes in pediatric gliomas Clinical and molecular characteristics of congenital glioblastoma Stabilization of HIF-1α and HIF-2α, up-regulation of MYCC and accumulation of stabilized p53 constitute hallmarks of CNS-PNET animal model YB-1 is a Transcription/Translation Factor that Orchestrates the Oncogenome by Hardwiring Signal Transduction to Gene Expression Biologically targeted therapeutics in pediatric brain tumors.Diagnostic and therapeutic stratification of childhood brain tumors: implications for translational research.Circulating tumor cells: detection, molecular profiling and future prospects.Phase I and pharmacokinetic studies of erlotinib administered concurrently with radiotherapy for children, adolescents, and young adults with high-grade glioma.Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells Pediatric Brain Tumors: Current Knowledge and Therapeutic Opportunities Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma.Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours.YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells.High-throughput microRNA profiling of pediatric high-grade gliomas.Histology and molecular pathology of pediatric brain tumors.Brain tumors across the age spectrum: biology, therapy, and late effects.

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Molecular profiling identifies prognostic subgroups of pediatric glioblastoma and shows increased YB-1 expression in tumors.

http://www.wikidata.org/entity/Q48221611

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Molecular profiling identifies ...... sed YB-1 expression in tumors.

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Molecular profiling identifies ...... sed YB-1 expression in tumors.

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Molecular profiling identifies ...... sed YB-1 expression in tumors.

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André Nantel

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Anne-Sophie Carret

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Damien Faury

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Enrique Lopez-Aguilar

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László Bognár

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Marie-Christine Guiot

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Martin Gleave

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