Inherited cortical HCN1 channel loss amplifies dendritic calcium electrogenesis and burst firing in a rat absence epilepsy model.
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Dynamic Network Connectivity: A new form of neuroplasticityHCN1 channel subunits are a molecular substrate for hypnotic actions of ketamine.Searching for new targets for treatment of pediatric epilepsyAnatomy and physiology of the thick-tufted layer 5 pyramidal neuronAdvances on genetic rat models of epilepsy.Hcn1 is a tremorgenic genetic component in a rat model of essential tremorHomeostasis or channelopathy? Acquired cell type-specific ion channel changes in temporal lobe epilepsy and their antiepileptic potentialElevation in type I interferons inhibits HCN1 and slows cortical neuronal oscillationsPostnatal development of dendritic synaptic integration in rat neocortical pyramidal neuronsCNF1 Enhances Brain Energy Content and Counteracts Spontaneous Epileptiform Phenomena in Aged DBA/2J Mice.Homeostatic regulation of synaptic excitability: tonic GABA(A) receptor currents replace I(h) in cortical pyramidal neurons of HCN1 knock-out mice.Subunit-specific effects of isoflurane on neuronal Ih in HCN1 knockout mice.Absence epilepsy in apathetic, a spontaneous mutant mouse lacking the h channel subunit, HCN2Loss of dendritic HCN1 subunits enhances cortical excitability and epileptogenesis.Selective participation of somatodendritic HCN channels in inhibitory but not excitatory synaptic integration in neurons of the subthalamic nucleus.Reduction of thalamic and cortical Ih by deletion of TRIP8b produces a mouse model of human absence epilepsy.Abnormal pyramidal cell morphology and HCN channel expression in cortical dysplasia.Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease.HCN channels in behavior and neurological disease: too hyper or not active enough?Distribution and function of HCN channels in the apical dendritic tuft of neocortical pyramidal neuronsThe fast and slow ups and downs of HCN channel regulation.Differential modulation of repetitive firing and synchronous network activity in neocortical interneurons by inhibition of A-type K(+) channels and Ih.Decreased hyperpolarization-activated currents in layer 5 pyramidal neurons enhances excitability in focal cortical dysplasia.Corticospinal-specific HCN expression in mouse motor cortex: I(h)-dependent synaptic integration as a candidate microcircuit mechanism involved in motor controlActivation of InsP₃ receptors is sufficient for inducing graded intrinsic plasticity in rat hippocampal pyramidal neurons.HCN channelopathies: pathophysiology in genetic epilepsy and therapeutic implicationsUnilateral and Bilateral Cortical Resection: Effects on Spike-Wave Discharges in a Genetic Absence Epilepsy Model.An N-terminal deletion variant of HCN1 in the epileptic WAG/Rij strain modulates HCN current densities.Impaired hippocampal rhythmogenesis in a mouse model of mesial temporal lobe epilepsyFunctional maps within a single neuron.Neurochemical and behavioral features in genetic absence epilepsy and in acutely induced absence seizures.Regulation of epileptiform discharges in rat neocortex by HCN channelsMutation analysis of the hyperpolarization-activated cyclic nucleotide-gated channels HCN1 and HCN2 in idiopathic generalized epilepsy.Effect of voltage sensitive fluorescent proteins on neuronal excitability.Hyperpolarization activated cyclic-nucleotide gated (HCN) channels in developing neuronal networks.A role for the preoptic sleep-promoting system in absence epilepsy.Covariation of axon initial segment location and dendritic tree normalizes the somatic action potential.Towards an integrated view of HCN channel role in epilepsy.HCN and KV7 (M-) channels as targets for epilepsy treatment.
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P2860
Inherited cortical HCN1 channel loss amplifies dendritic calcium electrogenesis and burst firing in a rat absence epilepsy model.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
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2006年學術文章
@zh-hant
name
Inherited cortical HCN1 channe ...... a rat absence epilepsy model.
@en
Inherited cortical HCN1 channe ...... a rat absence epilepsy model.
@nl
type
label
Inherited cortical HCN1 channe ...... a rat absence epilepsy model.
@en
Inherited cortical HCN1 channe ...... a rat absence epilepsy model.
@nl
prefLabel
Inherited cortical HCN1 channe ...... a rat absence epilepsy model.
@en
Inherited cortical HCN1 channe ...... a rat absence epilepsy model.
@nl
P2093
P2860
P1476
Inherited cortical HCN1 channe ...... a rat absence epilepsy model.
@en
P2093
Anja U Bräuer
Greg J Stuart
Maarten H P Kole
P2860
P304
P356
10.1113/JPHYSIOL.2006.122028
P407
P577
2006-11-09T00:00:00Z