Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model.
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Matricellular proteins: a sticky affair with cancersAcquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expressionSPARC Promotes Cell Invasion In Vivo by Decreasing Type IV Collagen Levels in the Basement MembraneADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic propertiesThe potential of GPNMB as novel neuroprotective factor in amyotrophic lateral sclerosisOsteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activityGrowth and repair factors, osteoactivin, matrix metalloproteinase and heat shock protein 72, increase with resolution of inflammation in musculotendinous tissues in a rat model of repetitive graspingSPARC is a key regulator of proliferation, apoptosis and invasion in human ovarian cancer.Genetic context determines susceptibility to intraocular pressure elevation in a mouse pigmentary glaucomaSPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-2'deoxycytidine to increase SPARC expression and improve therapy response.Bioinformatic and statistical analysis of the optic nerve head in a primate model of ocular hypertension.Expressions of the γ2 chain of laminin-5 and secreted protein acidic and rich in cysteine in esophageal squamous cell carcinoma and their relation to prognosis.Prospectively isolated cancer-associated CD10(+) fibroblasts have stronger interactions with CD133(+) colon cancer cells than with CD133(-) cancer cells.Affinity-matured anti-glycoprotein NMB recombinant immunotoxins targeting malignant gliomas and melanomas.KLF4 inhibition of lung cancer cell invasion by suppression of SPARC expression.PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration by suppressing SHC-RAF-ERK and AKT signaling.Genomic profiling of rectal adenoma and carcinoma by array-based comparative genomic hybridizationInhibition of Phosphatase Activity Follows Decline in Sulfatase Activity and Leads to Transcriptional Effects through Sustained Phosphorylation of Transcription Factor MITF.Proteolysis of the matricellular protein hevin by matrix metalloproteinase-3 produces a SPARC-like fragment (SLF) associated with neovasculature in a murine glioma model.Deletion of the SPARC acidic domain or EGF-like module reduces SPARC-induced migration and signaling through p38 MAPK/HSP27 in glioma.Glycoprotein nonmetastatic melanoma protein B extracellular fragment shows neuroprotective effects and activates the PI3K/Akt and MEK/ERK pathways via the Na+/K+-ATPase.SPARC upregulates MT1-MMP expression, MMP-2 activation, and the secretion and cleavage of galectin-3 in U87MG glioma cells.RNA interference against SPARC promotes the growth of U-87MG human malignant glioma cells.Beneficial impact of Gpnmb and its significance as a biomarker in nonalcoholic steatohepatitisStabilin-1 expression in tumor associated macrophages.Role of human HGFIN/nmb in breast cancerOsteoactivin/HGFIN: is it a tumor suppressor or mediator of metastasis in breast cancer?Melanoma-derived conditioned media efficiently induce the differentiation of monocytes to macrophages that display a highly invasive gene signature.Phase I/II study of the antibody-drug conjugate glembatumumab vedotin in patients with advanced melanoma.The PKD domain distinguishes the trafficking and amyloidogenic properties of the pigment cell protein PMEL and its homologue GPNMB.Glycoprotein non-metastatic b (GPNMB): A metastatic mediator and emerging therapeutic target in cancer.Tumor-associated macrophages as incessant builders and destroyers of the cancer stroma.SPARC: a matricellular regulator of tumorigenesis.Emerging therapeutic targets in breast cancer bone metastasis.The use of an antibody drug conjugate, glembatumumab vedotin (CDX-011), for the treatment of breast cancer.Management of metastatic breast cancer with second-generation antibody-drug conjugates: focus on glembatumumab vedotin (CDX-011, CR011-vcMMAE).Astrocyte-secreted matricellular proteins in CNS remodelling during development and diseaseKnocking down glycoprotein nonmetastatic melanoma protein B suppresses the proliferation, migration, and invasion in bladder cancer cells.Secreted Protein Acidic and Rich in Cysteine Modulates Molecular Arterial Homeostasis of Human Arterial Smooth Muscle Cells In Vitro.MiR-508-5p Inhibits the Progression of Glioma by Targeting Glycoprotein Non-metastatic Melanoma B.
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P2860
Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Bone-related genes expressed i ...... ly defined human cancer model.
@en
Bone-related genes expressed i ...... ly defined human cancer model.
@nl
type
label
Bone-related genes expressed i ...... ly defined human cancer model.
@en
Bone-related genes expressed i ...... ly defined human cancer model.
@nl
prefLabel
Bone-related genes expressed i ...... ly defined human cancer model.
@en
Bone-related genes expressed i ...... ly defined human cancer model.
@nl
P2093
P2860
P356
P1476
Bone-related genes expressed i ...... ly defined human cancer model.
@en
P2093
Chien-Tsun Kuan
Christopher M Counter
Jeremy N Rich
Mark Hjelmeland
Thomas J Cummings
Xiao-Fan Wang
P2860
P304
15951-15957
P356
10.1074/JBC.M211498200
P407
P577
2003-02-17T00:00:00Z