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Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complexCompeting E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasmNuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitorMaintaining Genome Stability in Defiance of Mitotic DNA DamageInsights into APC/C: from cellular function to diseases and therapeuticsThe recognition of ubiquitinated proteins by the proteasomeUbiquitin-Mediated Degradation of Aurora KinasesMotif co-regulation and co-operativity are common mechanisms in transcriptional, post-transcriptional and post-translational regulationThe multifaceted roles of the HORMA domain in cellular signalingReconstituting the kinetochore–microtubule interface: what, why, and howMitotic exit and separation of mother and daughter cellsFeedback loops and reciprocal regulation: recurring motifs in the systems biology of the cell cycleThe 3' untranslated region of the cyclin B mRNA is not sufficient to enhance the synthesis of cyclin B during a mitotic block in human cellsAtomic structure of the APC/C and its mechanism of protein ubiquitination.Interphase APC/C-Cdc20 inhibition by cyclin A2-Cdk2 ensures efficient mitotic entry.The kinetochore protein Kis1/Eic1/Mis19 ensures the integrity of mitotic spindles through maintenance of kinetochore factors Mis6/CENP-I and CENP-AThe zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylationThe Four Canonical TPR Subunits of Human APC/C Form Related Homo-Dimeric Structures and Stack in Parallel to Form a TPR SuprahelixInsights into Degron Recognition by APC/C Coactivators from the Structure of an Acm1-Cdh1 ComplexCmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control.The unconventional kinetoplastid kinetochore: from discovery toward functional understandingSpatiotemporal regulation of the anaphase-promoting complex in mitosisA minimal anaphase promoting complex/cyclosome (APC/C) in Trypanosoma bruceiExperimental validation of Ankrd17 and Anapc10, two novel meiotic genes predicted by computational models in miceA proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cellsSpatiotemporal organization of Aurora-B by APC/CCdh1 after mitosis coordinates cell spreading through FHOD1.Sequestration of CDH1 by MAD2L2 prevents premature APC/C activation prior to anaphase onset.The spindle assembly checkpoint works like a rheostat rather than a toggle switchUsing gene expression data to identify certain gastro-intestinal diseases.Expression of HSF2 decreases in mitosis to enable stress-inducible transcription and cell survival.Multiple mechanisms determine the order of APC/C substrate degradation in mitosis.Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C.The NOXA-MCL1-BIM axis defines lifespan on extended mitotic arrestMolecular architecture and mechanism of the anaphase-promoting complexDistinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint.Molecular mechanism of APC/C activation by mitotic phosphorylation.The kinetochore-dependent and -independent formation of the CDC20-MAD2 complex and its functions in HeLa cellsAPC/CCdh1 Enables Removal of Shugoshin-2 from the Arms of Bivalent Chromosomes by Moderating Cyclin-Dependent Kinase Activity.Conditional targeting of MAD1 to kinetochores is sufficient to reactivate the spindle assembly checkpoint in metaphase.Dynamic expression profiles from static cytometry data: component fitting and conversion to relative, "same scale" values
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
Cubism and the cell cycle: the many faces of the APC/C.
@en
Cubism and the cell cycle: the many faces of the APC/C.
@nl
type
label
Cubism and the cell cycle: the many faces of the APC/C.
@en
Cubism and the cell cycle: the many faces of the APC/C.
@nl
prefLabel
Cubism and the cell cycle: the many faces of the APC/C.
@en
Cubism and the cell cycle: the many faces of the APC/C.
@nl
P356
P1476
Cubism and the cell cycle: the many faces of the APC/C.
@en
P2888
P304
P356
10.1038/NRM3132
P577
2011-06-02T00:00:00Z