Characterization of the selectivity filter of the epithelial sodium channel.
about
Differential effects of Hsc70 and Hsp70 on the intracellular trafficking and functional expression of epithelial sodium channelsInherent dynamics of the acid-sensing ion channel 1 correlates with the gating mechanismX-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective ChannelEpithelial sodium channel (ENaC) family: Phylogeny, structure-function, tissue distribution, and associated inherited diseasesASIC and ENaC type sodium channels: conformational states and the structures of the ion selectivity filtersPlasmin activates epithelial Na+ channels by cleaving the gamma subunit.Epithelial sodium channel pore region. structure and role in gating.Comparative molecular biological analysis of membrane transport genes in organismsA selectivity filter at the intracellular end of the acid-sensing ion channel pore.Extracellular allosteric regulatory subdomain within the gamma subunit of the epithelial Na+ channel.Role of epithelial sodium channels and their regulators in hypertension.Defining an inhibitory domain in the gamma subunit of the epithelial sodium channelBase of the thumb domain modulates epithelial sodium channel gating.The DEG/ENaC protein MEC-10 regulates the transduction channel complex in Caenorhabditis elegans touch receptor neuronsENaC structure and function in the wake of a resolved structure of a family member.TMPRSS4-dependent activation of the epithelial sodium channel requires cleavage of the γ-subunit distal to the furin cleavage siteCurrent and selectivity in a model sodium channel under physiological conditions: Dynamic Monte Carlo simulations.Contribution of residues in second transmembrane domain of ASIC1a protein to ion selectivity.Structural basis for the selective permeability of channels made of communicating junction proteins.Multiple residues in the distal C terminus of the α-subunit have roles in modulating human epithelial sodium channel activity.Identification of the Ca2+ blocking site of acid-sensing ion channel (ASIC) 1: implications for channel gatingHypertonicity-induced cation channels.Gamma subunit second transmembrane domain contributes to epithelial sodium channel gating and amiloride block.Structure, function, and pharmacology of acid-sensing ion channels (ASICs): focus on ASIC1a.Insight into DEG/ENaC channel gating from genetics and structure.Ca2+ permeability and Na+ conductance in cellular toxicity caused by hyperactive DEG/ENaC channels.Epithelial sodium channel exit from the endoplasmic reticulum is regulated by a signal within the carboxyl cytoplasmic domain of the alpha subunit.Effect of divalent heavy metals on epithelial Na+ channels in A6 cells.The epithelial Na+ channel is inhibited by a peptide derived from proteolytic processing of its alpha subunit.Zinc is a voltage-dependent blocker of native and heterologously expressed epithelial Na+ channels.Novel determinants of epithelial sodium channel gating within extracellular thumb domains.Restoration of Epithelial Sodium Channel Function by Synthetic Peptides in Pseudohypoaldosteronism Type 1B Mutants.Characterization of an amiloride binding region in the alpha-subunit of ENaC.Candidate amino acids involved in H+ gating of acid-sensing ion channel 1a.Mutations in the pore region modify epithelial sodium channel gating by shear stress.External nickel inhibits epithelial sodium channel by binding to histidine residues within the extracellular domains of alpha and gamma subunits and reducing channel open probability.Point mutations in the post-M2 region of human alpha-ENaC regulate cation selectivity.Second transmembrane domains of ENaC subunits contribute to ion permeation and selectivity.An external site controls closing of the epithelial Na+ channel ENaC.Asymmetric organization of the pore region of the epithelial sodium channel.
P2860
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P2860
Characterization of the selectivity filter of the epithelial sodium channel.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh-hant
name
Characterization of the selectivity filter of the epithelial sodium channel.
@en
Characterization of the selectivity filter of the epithelial sodium channel.
@nl
type
label
Characterization of the selectivity filter of the epithelial sodium channel.
@en
Characterization of the selectivity filter of the epithelial sodium channel.
@nl
prefLabel
Characterization of the selectivity filter of the epithelial sodium channel.
@en
Characterization of the selectivity filter of the epithelial sodium channel.
@nl
P2093
P2860
P356
P1476
Characterization of the selectivity filter of the epithelial sodium channel.
@en
P2093
P2860
P304
P356
10.1074/JBC.275.12.8572
P407
P577
2000-03-01T00:00:00Z