Properties of human glycine receptors containing the hyperekplexia mutation alpha1(K276E), expressed in Xenopus oocytes.
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Kinetic determinants of agonist action at the recombinant human glycine receptorTaking the time to study competitive antagonismThe impact of human hyperekplexia mutations on glycine receptor structure and functionActivation of human alpha1 and alpha2 homomeric glycine receptors by taurine and GABASignal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion ChannelsRole of charged residues in coupling ligand binding and channel activation in the extracellular domain of the glycine receptor.Murine startle mutant Nmf11 affects the structural stability of the glycine receptor and increases deactivation.Glycine receptor mouse mutants: model systems for human hyperekplexiaβ Subunit M2-M3 loop conformational changes are uncoupled from α1 β glycine receptor channel gating: implications for human hereditary hyperekplexia.Genetics, an alternative way to discover, characterize and understand ion channels.NMR structures of the second transmembrane domain of the human glycine receptor alpha(1) subunit: model of pore architecture and channel gating.Charged residues at the 2' position of human GABAC rho 1 receptors invert ion selectivity and influence open state probability.The neuronal channelopathies.Correlating structural and energetic changes in glycine receptor activation.Agonist-activated ion channels.Inhibitory glycine receptors: an update.The extracellular linker of muscle acetylcholine receptor channels is a gating control element.Openings of the rat recombinant alpha 1 homomeric glycine receptor as a function of the number of agonist molecules boundSingle channel analysis of conductance and rectification in cation-selective, mutant glycine receptor channelsInvestigating the Mechanism by Which Gain-of-function Mutations to the α1 Glycine Receptor Cause Hyperekplexia.Glycine Receptors Caught between Genome and Proteome - Functional Implications of RNA Editing and Splicing.What single-channel analysis tells us of the activation mechanism of ligand-gated channels: the case of the glycine receptor.The structural basis of function in Cys-loop receptors.The structural mechanism of the Cys-loop receptor desensitization.Chloride ions in the pore of glycine and GABA channels shape the time course and voltage dependence of agonist currents.The kinetics of inhibition of rat recombinant heteromeric alpha1beta glycine receptors by the low-affinity antagonist SR-95531.Investigation of the alpha(1)-glycine receptor channel-opening kinetics in the submillisecond time domain.The pre-M1 segment of the alpha1 subunit is a transduction element in the activation of the GABAA receptor.Role of aspartate 298 in mouse 5-HT3A receptor gating and modulation by extracellular Ca2+.Characterization of a glycine receptor domain that controls the binding and gating mechanisms of the beta-amino acid agonist, taurine.Opposing effects of molecular volume and charge at the hyperekplexia site alpha 1(P250) govern glycine receptor activation and desensitization.Arg-274 and Leu-277 of the gamma-aminobutyric acid type A receptor alpha 2 subunit define agonist efficacy and potency.Kinetic and mutational analysis of Zn2+ modulation of recombinant human inhibitory glycine receptors.Differential regulation of NMDA receptors by d-serine and glycine in mammalian spinal locomotor networks.The Startle Disease Mutation E103K Impairs Activation of Human Homomeric α1 Glycine Receptors by Disrupting an Intersubunit Salt Bridge across the Agonist Binding Site.Novel regulatory site within the TM3-4 loop of human recombinant alpha3 glycine receptors determines channel gating and domain structure.Cloning and functional characterization of two glycine receptor alpha-subunits from the perch retina.Functional characterization of compound heterozygosity for GlyRalpha1 mutations in the startle disease hyperekplexia.GABA(A) receptor M2-M3 loop secondary structure and changes in accessibility during channel gating.A basic cluster determines topology of the cytoplasmic M3-M4 loop of the glycine receptor alpha1 subunit.
P2860
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P2860
Properties of human glycine receptors containing the hyperekplexia mutation alpha1(K276E), expressed in Xenopus oocytes.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Properties of human glycine re ...... expressed in Xenopus oocytes.
@en
Properties of human glycine re ...... expressed in Xenopus oocytes.
@nl
type
label
Properties of human glycine re ...... expressed in Xenopus oocytes.
@en
Properties of human glycine re ...... expressed in Xenopus oocytes.
@nl
altLabel
Properties of human glycine re ...... , expressed in Xenopus oocytes
@en
prefLabel
Properties of human glycine re ...... expressed in Xenopus oocytes.
@en
Properties of human glycine re ...... expressed in Xenopus oocytes.
@nl
P2093
P2860
P1476
Properties of human glycine re ...... expressed in Xenopus oocytes.
@en
P2093
D Colquhoun
R M Gardiner
R Schoepfer
P2860
P356
10.1111/J.1469-7793.1998.025BU.X
P407
P478
507 ( Pt 1)
P577
1998-02-01T00:00:00Z