Kinetic and mutational analysis of Zn2+ modulation of recombinant human inhibitory glycine receptors.
about
Kinetic determinants of agonist action at the recombinant human glycine receptorDifferential agonist sensitivity of glycine receptor alpha2 subunit splice variantsModulation of extrasynaptic NMDA receptors by synaptic and tonic zinc.Formation of NR1/NR2 and NR1/NR3 heterodimers constitutes the initial step in N-methyl-D-aspartate receptor assembly.Molecular basis for zinc potentiation at strychnine-sensitive glycine receptorsZinc-dependent modulation of α2- and α3-glycine receptor subunits by ethanol.Two gamma2L subunit domains confer low Zn2+ sensitivity to ternary GABA(A) receptorsMurine startle mutant Nmf11 affects the structural stability of the glycine receptor and increases deactivation.Tonic zinc inhibits spontaneous firing in dorsal cochlear nucleus principal neurons by enhancing glycinergic neurotransmission.Glycine receptor mouse mutants: model systems for human hyperekplexiaMutation of a zinc-binding residue in the glycine receptor α1 subunit changes ethanol sensitivity in vitro and alcohol consumption in vivoGlycine receptor mutants of the mouse: what are possible routes of inhibitory compensation?Allosteric modulation of glycine receptors.Extracellular pH modulates GABAergic neurotransmission in rat hypothalamus.Zinc enhances ethanol modulation of the alpha1 glycine receptor.Molecular determinants of proton modulation of glycine receptors.Minimal structural rearrangement of the cytoplasmic pore during activation of the 5-HT3A receptor.Characteristics of glycine receptors expressed by embryonic rat brain mRNAs.Zinc modulation of glycine receptorsZn2+ ions: modulators of excitatory and inhibitory synaptic activity.Openings of the rat recombinant alpha 1 homomeric glycine receptor as a function of the number of agonist molecules boundSingle channel analysis of conductance and rectification in cation-selective, mutant glycine receptor channelsFast synaptic inhibition in spinal sensory processing and pain control.Identification of Parvalbumin Interneurons as Cellular Substrate of Fear Memory Persistence.Functional modulation of glycine receptors by the alkaloid gelsemine.Single-channel analysis of ethanol enhancement of glycine receptor functionPropofol modulation of α1 glycine receptors does not require a structural transition at adjacent subunits that is crucial to agonist-induced activationPhysiological concentrations of zinc reduce taurine-activated GlyR responses to drugs of abuse.Contaminating levels of zinc found in commonly-used labware and buffers affect glycine receptor currents.Structure and Pharmacologic Modulation of Inhibitory Glycine Receptors.Allosteric modulation of the glycine receptor activated by agonists differing in efficacy.Mapping a molecular link between allosteric inhibition and activation of the glycine receptor.Molecular determinants of glycine receptor alphabeta subunit sensitivities to Zn2+-mediated inhibition.Insights into the structural basis for zinc inhibition of the glycine receptor.An N-terminal histidine regulates Zn(2+) inhibition on the murine GABA(A) receptor beta3 subunitCharacterization of a glycine receptor domain that controls the binding and gating mechanisms of the beta-amino acid agonist, taurine.Ethanol enhances taurine-activated glycine receptor function.Zinc as a Neuromodulator in the Central Nervous System with a Focus on the Olfactory Bulb.Disruption of interdomain interactions in the glutamate binding pocket affects differentially agonist affinity and efficacy of N-methyl-D-aspartate receptor activation.Zinc inactivates melastatin transient receptor potential 2 channels via the outer pore.
P2860
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P2860
Kinetic and mutational analysis of Zn2+ modulation of recombinant human inhibitory glycine receptors.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Kinetic and mutational analysi ...... inhibitory glycine receptors.
@en
type
label
Kinetic and mutational analysi ...... inhibitory glycine receptors.
@en
prefLabel
Kinetic and mutational analysi ...... inhibitory glycine receptors.
@en
P2093
P2860
P1476
Kinetic and mutational analysi ...... inhibitory glycine receptors.
@en
P2093
P2860
P304
P356
10.1111/J.1469-7793.2000.T01-1-00215.X
P407
P478
P577
2000-01-01T00:00:00Z