Rho kinase inhibitor fasudil protects against β-amyloid-induced hippocampal neurodegeneration in rats.
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Non-muscle myosin II in disease: mechanisms and therapeutic opportunitiesThe ROCK Inhibitor Fasudil Prevents Chronic Restraint Stress-Induced Depressive-Like Behaviors and Dendritic Spine Loss in Rat HippocampusAPC/CCdh1-Rock2 pathway controls dendritic integrity and memory.HIV-1 Tat activates a RhoA signaling pathway to reduce NMDA-evoked calcium responses in hippocampal neurons via an actin-dependent mechanismTranscriptomic analysis and 3D bioengineering of astrocytes indicate ROCK inhibition produces cytotrophic astrogliosis.FSD-C10: A more promising novel ROCK inhibitor than Fasudil for treatment of CNS autoimmunity.Effects of Rho Kinase Inhibitors on Grafts of Dopaminergic Cell Precursors in a Rat Model of Parkinson's Disease.RhoA Signaling and Synaptic Damage Occur Within Hours in a Live Pig Model of CNS Injury, Retinal Detachment.Correlation between platelet-derived growth factor signaling pathway and inflammation in desoxycorticosterone-induced salt-sensitive hypertensive rats with myocardial fibrosis.In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state.Fasudil, an inhibitor of Rho-associated coiled-coil kinase, improves cognitive impairments induced by smoke exposure.Rho kinase II interference by small hairpin RNA ameliorates 1‑methyl‑4‑phenyl‑1,2,3,6‑tetrahydropyridine‑induced parkinsonism in mice.Hippocampal CysLT1R knockdown or blockade represses LPS-induced depressive behaviors and neuroinflammatory response in mice.Neuroinflammation in Alzheimer's disease: an understanding of physiology and pathology.The potential role of rho GTPases in Alzheimer's disease pathogenesis.Function of Nogo-A/Nogo-A receptor in Alzheimer's disease.Rho-associated protein kinase 2 (ROCK2): a new target of autoimmunity in paraneoplastic encephalitis.Chatting with the neighbors: crosstalk between Rho-kinase (ROCK) and other signaling pathways for treatment of neurological disorders.Interaction between NADPH-oxidase and Rho-kinase in angiotensin II-induced microglial activation.Rho-associated protein kinases as therapeutic targets for both vascular and parenchymal pathologies in Alzheimer's disease.RhoA-ROCK Inhibition Reverses Synaptic Remodeling and Motor and Cognitive Deficits Caused by Traumatic Brain Injury.PEG-PEI/siROCK2 Protects Against Aβ42-Induced Neurotoxicity in Primary Neuron Cells for Alzheimer Disease.Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil.Serum Klotho, vitamin D, and homocysteine in combination predict the outcomes of Chinese patients with multiple system atrophy.Protective Effects of Baicalin on Aβ₁₋₄₂-Induced Learning and Memory Deficit, Oxidative Stress, and Apoptosis in Rat.Fasudil mediates cell therapy of EAE by immunomodulating encephalomyelitic T cells and macrophages.The therapeutic potential of Rho kinase inhibitor fasudil derivative FaD-1 in experimental autoimmune encephalomyelitis.Inhibition of Rho-kinase by Fasudil protects dopamine neurons and attenuates inflammatory response in an intranasal lipopolysaccharide-mediated Parkinson's model.Therapeutic effect of Rho kinase inhibitor FSD-C10 in a mouse model of Alzheimer's diseaseA role for APP in Wnt signalling links synapse loss with β-amyloid production
P2860
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P2860
Rho kinase inhibitor fasudil protects against β-amyloid-induced hippocampal neurodegeneration in rats.
description
2013 nî lūn-bûn
@nan
2013年の論文
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2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
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2013年學術文章
@yue
2013年學術文章
@zh-hant
name
Rho kinase inhibitor fasudil p ...... pal neurodegeneration in rats.
@en
Rho kinase inhibitor fasudil p ...... pal neurodegeneration in rats.
@nl
type
label
Rho kinase inhibitor fasudil p ...... pal neurodegeneration in rats.
@en
Rho kinase inhibitor fasudil p ...... pal neurodegeneration in rats.
@nl
prefLabel
Rho kinase inhibitor fasudil p ...... pal neurodegeneration in rats.
@en
Rho kinase inhibitor fasudil p ...... pal neurodegeneration in rats.
@nl
P2093
P2860
P356
P1476
Rho kinase inhibitor fasudil p ...... mpal neurodegeneration in rats
@en
P2093
P2860
P304
P356
10.1111/CNS.12116
P577
2013-05-03T00:00:00Z