The thioesterase domain from the pimaricin and erythromycin biosynthetic pathways can catalyze hydrolysis of simple thioester substrates.
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Different active-site loop orientation in serine hydrolases versus acyltransferasesStructural Studies of an A2-Type Modular Polyketide Synthase Ketoreductase Reveal Features Controlling α-Substituent StereochemistrySelective removal of aberrant extender units by a type II thioesterase for efficient FR-008/candicidin biosynthesis in Streptomyces sp. strain FR-008.Structural analysis of protein-protein interactions in type I polyketide synthasesThe structures of type I polyketide synthases.Polyketide synthase and non-ribosomal peptide synthetase thioesterase selectivity: logic gate or a victim of fate?Comparative characterization of fungal anthracenone and naphthacenedione biosynthetic pathways reveals an α-hydroxylation-dependent Claisen-like cyclization catalyzed by a dimanganese thioesterase.The biochemical basis for stereochemical control in polyketide biosynthesis.Enantio- and diastereoselective intermolecular Stetter reaction of glyoxamide and alkylidene ketoamides.Substrate structure-activity relationships guide rational engineering of modular polyketide synthase ketoreductases.A thioesterase from an iterative fungal polyketide synthase shows macrocyclization and cross coupling activity and may play a role in controlling iterative cycling through product offloading.Mutant malonyl-CoA synthetases with altered specificity for polyketide synthase extender unit generation.Divergent mechanistic routes for the formation of gem-dimethyl groups in the biosynthesis of complex polyketides.Engineered polyketides: Synergy between protein and host level engineering.
P2860
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P2860
The thioesterase domain from the pimaricin and erythromycin biosynthetic pathways can catalyze hydrolysis of simple thioester substrates.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
The thioesterase domain from t ...... f simple thioester substrates.
@en
The thioesterase domain from t ...... f simple thioester substrates.
@nl
type
label
The thioesterase domain from t ...... f simple thioester substrates.
@en
The thioesterase domain from t ...... f simple thioester substrates.
@nl
prefLabel
The thioesterase domain from t ...... f simple thioester substrates.
@en
The thioesterase domain from t ...... f simple thioester substrates.
@nl
P1476
The thioesterase domain from t ...... f simple thioester substrates.
@en
P2093
Krishna K Sharma
P304
P356
10.1016/J.BMCL.2007.03.060
P407
P577
2007-03-23T00:00:00Z