The PEA15 gene is overexpressed and related to insulin resistance in healthy first-degree relatives of patients with type 2 diabetes.
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On the Quest of Cellular Functions of PEA-15 and the Therapeutic OpportunitiesBisphenol-A impairs insulin action and up-regulates inflammatory pathways in human subcutaneous adipocytes and 3T3-L1 cellsPreliminary data on effects of metformin on PED/PEA-15 cellular levels in obese women with polycystic ovary syndrome.Phosphoprotein enriched in astrocytes (PEA)-15: a potential therapeutic target in multiple disease states.Adenoviral gene transfer of PLD1-D4 enhances insulin sensitivity in mice by disrupting phospholipase D1 interaction with PED/PEA-15.Serum 25-Hydroxyvitamin D Levels, phosphoprotein enriched in diabetes gene product (PED/PEA-15) and leptin-to-adiponectin ratio in women with PCOSClozapine impairs insulin action by up-regulating Akt phosphorylation and Ped/Pea-15 protein abundance.PED/PEA-15 induces autophagy and mediates TGF-beta1 effect on muscle cell differentiationPeroxisome proliferator-activated receptor-γ activation enhances insulin-stimulated glucose disposal by reducing ped/pea-15 gene expression in skeletal muscle cells: evidence for involvement of activator protein-1Targetting PED/PEA-15 for diabetes treatment.PED/PEA-15 controls fibroblast motility and wound closure by ERK1/2-dependent mechanisms.Parkinson-like phenotype in insulin-resistant PED/PEA-15 transgenic mice.NMR backbone dynamics studies of human PED/PEA-15 outline protein functional sites.Effect of physical training on insulin secretion and action in skeletal muscle and adipose tissue of first-degree relatives of type 2 diabetic patients.Molecular cloning and characterization of the human PED/PEA-15 gene promoter reveal antagonistic regulation by hepatocyte nuclear factor 4alpha and chicken ovalbumin upstream promoter transcription factor II.Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells.
P2860
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P2860
The PEA15 gene is overexpressed and related to insulin resistance in healthy first-degree relatives of patients with type 2 diabetes.
description
2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
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2006年學術文章
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name
The PEA15 gene is overexpresse ...... patients with type 2 diabetes.
@en
The PEA15 gene is overexpresse ...... patients with type 2 diabetes.
@nl
type
label
The PEA15 gene is overexpresse ...... patients with type 2 diabetes.
@en
The PEA15 gene is overexpresse ...... patients with type 2 diabetes.
@nl
prefLabel
The PEA15 gene is overexpresse ...... patients with type 2 diabetes.
@en
The PEA15 gene is overexpresse ...... patients with type 2 diabetes.
@nl
P2093
P50
P1433
P1476
The PEA15 gene is overexpresse ...... patients with type 2 diabetes
@en
P2093
E Della Valle
E Farinaro
F Beguinot
G A Lupoli
G Donnarumma
G Riccardi
M Cardellini
M L Hribal
P2860
P2888
P304
P356
10.1007/S00125-006-0455-5
P577
2006-10-05T00:00:00Z