Transcription deregulation at the 15q25 locus in association with lung adenocarcinoma risk.
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Meta-analysis and imputation refines the association of 15q25 with smoking quantityThe Oncogenic Functions of Nicotinic Acetylcholine ReceptorsUpdates on the COPD gene listGenetic susceptibility to lung cancer--light at the end of the tunnel?New mechanisms and perspectives in nicotine withdrawalMultiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.Quantitative analysis of the heteromeric neuronal nicotinic receptors in the rat hippocampusGenetics of sputum gene expression in chronic obstructive pulmonary diseaseChromosome 15q25 (CHRNA3-CHRNA5) variation impacts indirectly on lung cancer riskGenome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstructionCHRNA3 polymorphism modifies lung adenocarcinoma risk in the Chinese Han populationFine mapping of chromosome 15q25.1 lung cancer susceptibility in African-Americans.Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25.Nicotinic α5 receptor subunit mRNA expression is associated with distant 5' upstream polymorphisms.Genetic variations on chromosomes 5p15 and 15q25 and bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control studySusceptibility loci for lung cancer are associated with mRNA levels of nearby genes in the lung.Chromosome 15q24-25.1 variants, diet, and lung cancer susceptibility in cigarette smokersCis-regulatory variants affect CHRNA5 mRNA expression in populations of African and European ancestry.CHRNA5 as negative regulator of nicotine signaling in normal and cancer bronchial cells: effects on motility, migration and p63 expression.Susceptibility loci in lung cancer and COPD: association of IREB2 and FAM13A with pulmonary diseases.The role of haplotype in 15q25.1 locus in lung cancer risk: results of scanning chromosome 15.Unraveling the neurobiology of nicotine dependence using genetically engineered miceRisk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.Functional characterization of SNPs in CHRNA3/B4 intergenic region associated with drug behaviors.Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility geneFrom smoking to lung cancer: the CHRNA5/A3/B4 connection.Nicotine dependence may link the 15q25 locus to lung cancer risk.Genetic susceptibility variants for lung cancer: replication study and assessment as expression quantitative trait loci.Common pathogenic mechanisms and pathways in the development of COPD and lung cancer.The CHRNA5-A3-B4 gene cluster in nicotine addiction.α9- and α7-containing receptors mediate the pro-proliferative effects of nicotine in the A549 adenocarcinoma cell line.Selenium mediated arsenic toxicity modifies cytotoxicity, reactive oxygen species and phosphorylated proteins.Impact of human D398N single nucleotide polymorphism on intracellular calcium response mediated by α3β4α5 nicotinic acetylcholine receptors.Expression patterns for nicotinic acetylcholine receptor subunit genes in smoking-related lung cancers.Nicotinic acetylcholine receptors mediate lung cancer growth.Promoter polymorphisms and transcript levels of nicotinic receptor CHRNA5.Markers in the 15q24 nicotinic receptor subunit gene cluster (CHRNA5-A3-B4) predict severity of nicotine addiction and response to smoking cessation therapy.FAM13A as a Novel Hypoxia-Induced Gene in Non-Small Cell Lung Cancer.Overexpression of the CHRNA5/A3/B4 genomic cluster in mice increases the sensitivity to nicotine and modifies its reinforcing effects.Functional effect of polymorphisms in 15q25 locus on CHRNA5 mRNA, bulky DNA adducts and TP53 mutations.
P2860
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P2860
Transcription deregulation at the 15q25 locus in association with lung adenocarcinoma risk.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Transcription deregulation at ...... with lung adenocarcinoma risk.
@en
Transcription deregulation at ...... with lung adenocarcinoma risk.
@nl
type
label
Transcription deregulation at ...... with lung adenocarcinoma risk.
@en
Transcription deregulation at ...... with lung adenocarcinoma risk.
@nl
prefLabel
Transcription deregulation at ...... with lung adenocarcinoma risk.
@en
Transcription deregulation at ...... with lung adenocarcinoma risk.
@nl
P2093
P50
P1476
Transcription deregulation at ...... with lung adenocarcinoma risk
@en
P2093
Antonella Galvan
Elisa Calabrò
Felicia S Falvella
Matteo Incarbone
Monica Spinola
P304
P356
10.1158/1078-0432.CCR-08-2107
P407
P577
2009-02-17T00:00:00Z