Cucurbitacin: ancient compound shedding new light on cancer treatment.
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Cucurbitacin I inhibits cell motility by indirectly interfering with actin dynamicsCucurbitacin I Attenuates Cardiomyocyte Hypertrophy via Inhibition of Connective Tissue Growth Factor (CCN2) and TGF- β/Smads SignalingsCucurbitacin-I (JSI-124) activates the JNK/c-Jun signaling pathway independent of apoptosis and cell cycle arrest in B leukemic cells.GADD45γ induces G2/M arrest in human pharynx and nasopharyngeal carcinoma cells by cucurbitacin E.Cucurbitacin I blocks cerebrospinal fluid and platelet derived growth factor-BB stimulation of leptomeningeal and meningioma DNA synthesis.Cucurbitacins from the Leaves of Citrullus colocynthis (L.) Schrad.The effectiveness of cucurbitacin B in BRCA1 defective breast cancer cells.Cucurbitacin B induced ATM-mediated DNA damage causes G2/M cell cycle arrest in a ROS-dependent manner.Natural compounds as potential treatments of NF2-deficient schwannoma and meningioma: cucurbitacin D and goyazensolideEffects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis.Valuing the Endangered Species Antirrhinum lopesianum: Neuroprotective Activities and Strategies for in vitro Plant PropagationCucurbitacin I inhibits Rac1 activation in breast cancer cells by a reactive oxygen species-mediated mechanism and independently of Janus tyrosine kinase 2 and P-Rex1.Synergistic effect of low-dose cucurbitacin B and low-dose methotrexate for treatment of human osteosarcoma.Cucurbitacin E as inducer of cell death and apoptosis in human oral squamous cell carcinoma cell line SASHonokiol as a Radiosensitizing Agent for Colorectal cancers.Inducement of mitosis delay by cucurbitacin E, a novel tetracyclic triterpene from climbing stem of Cucumis melo L., through GADD45γ in human brain malignant glioma (GBM) 8401 cells.Current evidence on the anticancer potential of Chios mastic gum.Cancer stem cells, microRNAs, and therapeutic strategies including natural products.Terpenoids: natural products for cancer therapy.Cucurbitacins: A Systematic Review of the Phytochemistry and Anticancer Activity.Purification of Cucurbitacins D, E, and I from Ecballium Elaterium (L.) A. Rich Fruits and Study of Their Cytotoxic Effects on the AGS Cell LineCytotoxic effects of natural and semisynthetic cucurbitacins on lung cancer cell line A549.IL-17 promotes tumor angiogenesis through Stat3 pathway mediated upregulation of VEGF in gastric cancer.Structural optimization and biological screening of a steroidal scaffold possessing cucurbitacin-like functionalities as B-Raf inhibitors.Gastrointestinal toxicity due to bitter bottle gourd (Lagenaria siceraria)--a report of 15 cases.Isolation, structure elucidation, and biological evaluation of 16,23-epoxycucurbitacin constituents from Eleaocarpus chinensis.Cucurbitacin I inhibits tumorigenic ability and enhances radiochemosensitivity in nonsmall cell lung cancer-derived CD133-positive cells.Cucurbitacins: elucidation of their interactions with the cytoskeleton.Cucurbitacin covalent bonding to cysteine thiols: the filamentous-actin severing protein Cofilin1 as an exemplary targetA biotransformation process for the production of cucurbitacin B from its glycoside using a selected Streptomyces sp.Identification of Conserved and Diverse Metabolic Shift of the Stylar, Intermediate and Peduncular Segments of Cucumber Fruit during Development.Cucurbitacin B synergistically enhances the apoptosis-inducing effect of arsenic trioxide by inhibiting STAT3 phosphorylation in lymphoma Ramos cells.Cucurbitacin D Is a Disruptor of the HSP90 Chaperone Machinery.The cucurbitacins D, E, and I from Ecballium elaterium (L.) upregulate the LC3 gene and induce cell-cycle arrest in human gastric cancer cell line AGS.Focus on ADF/Cofilin: Beyond Actin Cytoskeletal Regulation
P2860
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P2860
Cucurbitacin: ancient compound shedding new light on cancer treatment.
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
@wuu
2010年学术文章
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2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
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2010年学术文章
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2010年學術文章
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2010年學術文章
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name
Cucurbitacin: ancient compound shedding new light on cancer treatment.
@en
Cucurbitacin: ancient compound shedding new light on cancer treatment.
@nl
type
label
Cucurbitacin: ancient compound shedding new light on cancer treatment.
@en
Cucurbitacin: ancient compound shedding new light on cancer treatment.
@nl
prefLabel
Cucurbitacin: ancient compound shedding new light on cancer treatment.
@en
Cucurbitacin: ancient compound shedding new light on cancer treatment.
@nl
P2093
P356
P1476
Cucurbitacin: ancient compound shedding new light on cancer treatment.
@en
P2093
Dhong Hyun Lee
Gabriela B Iwanski
Nils H Thoennissen
P304
P356
10.1100/TSW.2010.44
P407
P5008
P577
2010-03-05T00:00:00Z