HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. - Wikidata - awgldk - TriplyDB

HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding.

HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding.

http://www.wikidata.org/entity/Q52024405

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CD34+ hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation control CD44, Hyaluronan, the Hematopoietic Stem Cell, and Leukemia-Initiating Cells HES1 is a novel interactor of the Fanconi anemia core complex Path2enet: generation of human pathway-derived networks in an expression specific context.Spatial stochastic modelling of the Hes1 gene regulatory network: intrinsic noise can explain heterogeneity in embryonic stem cell differentiation.KSHV manipulates Notch signaling by DLL4 and JAG1 to alter cell cycle genes in lymphatic endothelia Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo.Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells Kruppel-like factor 4 is essential for inflammatory monocyte differentiation in vivo.Suppression of p53 by Notch3 is mediated by Cyclin G1 and sustained by MDM2 and miR-221 axis in hepatocellular carcinoma Targeting HIF1α eliminates cancer stem cells in hematological malignancies.MIR144 and MIR451 regulate human erythropoiesis via RAB14 HES1-mediated inhibition of Notch1 signaling by a Gemini vitamin D analog leads to decreased CD44(+)/CD24(-/low) tumor-initiating subpopulation in basal-like breast cancer.HES1 is an independent prognostic factor for acute myeloid leukemia.p63 regulates human keratinocyte proliferation via MYC-regulated gene network and differentiation commitment through cell adhesion-related gene network.TLR9 is important for protection against intestinal damage and for intestinal repair.γ-Secretase inhibition promotes cell death, Noxa upregulation, and sensitization to BH3 mimetic ABT-737 in human breast cancer cells.Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population Hes1 mediates the different responses of hematopoietic stem and progenitor cells to T cell leukemic environment Structure and function of the solid tumor niche.Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment Aryl Hydrocarbon Receptor Deficiency in an Exon 3 Deletion Mouse Model Promotes Hematopoietic Stem Cell Proliferation and Impacts Endosteal Niche Cells.Canonical notch signaling is dispensable for the maintenance of adult hematopoietic stem cells Epigenomic enhancer annotation reveals a key role for NFIX in neural stem cell quiescence.Notch-dependent differentiation of adult airway basal stem cells.The notch target gene HES1 regulates cell cycle inhibitor expression in the developing pituitary.Notch signaling in the hematopoietic system.Cell cycle regulation in hematopoietic stem cells.HES1 promotes metastasis and predicts poor survival in patients with colorectal cancer.Notch activation inhibits AML growth and survival: a potential therapeutic approach.Reciprocal upregulation of Notch signaling molecules in hematopoietic progenitor and mesenchymal stromal cells.Control of the reversibility of cellular quiescence by the transcriptional repressor HES1.Inhibition of Notch1 promotes hedgehog signalling in a HES1-dependent manner in chondrocytes and exacerbates experimental osteoarthritis.Expression of hairy/enhancer of split genes in neural progenitors and neurogenesis domains of the adult zebrafish brain.Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury.Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer.Transformation of mouse T cells requires MYC and AKT activity in conjunction with inhibition of intrinsic apoptosis.

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P2860

HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding.

http://www.wikidata.org/entity/Q52024405

description

2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

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2006年學術文章

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name

HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding.

@en

HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding.

@nl

type

label

HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding.

@en

HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding.

@nl

prefLabel

HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding.

@en

HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding.

@nl

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STEMCELLS.2005-0598

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HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding.

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Alan D Friedman

http://www.w3.org/2001/XMLSchema#string

Curt I Civin

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Jonathan K Alder

http://www.w3.org/2001/XMLSchema#string

Jong Ho Chun

http://www.w3.org/2001/XMLSchema#string

Shelly Heimfeld

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Xiaobing Yu

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P2860

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex

A natural classification of the basic helix-loop-helix class of transcription factors

CDK inhibitors: positive and negative regulators of G1-phase progression

Notch signaling: cell fate control and signal integration in development

Transcriptional coactivator complexes

HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo

Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

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876-888

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10.1634/STEMCELLS.2005-0598

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4

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