Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1.
about
Characteristics of Antisense Transcript Promoters and the Regulation of Their ActivityRegulatory gene network circuits underlying T cell development from multipotent progenitorsA functional screen to identify novel effectors of hematopoietic stem cell activityCell-type-specific activation and repression of PU.1 by a complex of discrete, functionally specialized cis-regulatory elementsA gene regulatory network armature for T lymphocyte specification.Transcriptional establishment of cell-type identity: dynamics and causal mechanisms of T-cell lineage commitment.Bcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network.Transcriptional repressor Gfi1 integrates cytokine-receptor signals controlling B-cell differentiation.Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia.A large gene network in immature erythroid cells is controlled by the myeloid and B cell transcriptional regulator PU.1.PU.1 and Haematopoietic Cell Fate: Dosage MattersPU.1 induces apoptosis in myeloma cells through direct transactivation of TRAILHematopoiesis in steady-state versus stress: self-renewal, lineage fate choice, and the conversion of danger signals into cytokine signals in hematopoietic stem cellsAssociation of a functional polymorphism in the 3'-untranslated region of SPI1 with systemic lupus erythematosus.Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells.Hematopoietic cytokines can instruct lineage choice.Using random walks to identify cancer-associated modules in expression dataRegulation of early T-lineage gene expression and developmental progression by the progenitor cell transcription factor PU.1.Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia.Nfix expression critically modulates early B lymphopoiesis and myelopoiesisA distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia.GATA-1 Inhibits PU.1 Gene via DNA and Histone H3K9 Methylation of Its Distal Enhancer in ErythroleukemiaJNK-dependent gene regulatory circuitry governs mesenchymal fate.Irreversibility of T-Cell Specification: Insights from Computational Modelling of a Minimal Network Architecture.The PU.1-Modulated MicroRNA-22 Is a Regulator of Monocyte/Macrophage Differentiation and Acute Myeloid Leukemia.C/EBPalpha binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment.RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.miR-146a and miR-155 Expression Levels in Acute Graft-Versus-Host Disease IncidencePerspectives of proteomics in acute myeloid leukemia.PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element.Sustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells.Analysis of concentration-dependent functions of PU.1 in hematopoiesis using mouse models.Epigenetic regulation of normal and malignant hematopoiesis.Launching the T-cell-lineage developmental programmeCompetition and collaboration: GATA-3, PU.1, and Notch signaling in early T-cell fate determination.The Role of miRNA in Haematological Malignancy.PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia.The role of PU.1 and GATA-1 transcription factors during normal and leukemogenic hematopoiesis.Multilayered specification of the T-cell lineage fate.
P2860
Q26772020-34652013-0E94-450C-A83E-BA0D831F6166Q26995184-68E93358-E07B-4CE5-AEFB-C54BC12024EEQ28513837-9FE6F69F-F4F2-4533-9D5A-4DA46D36EF66Q28748978-694A1086-3700-43E8-A2D5-267F580BD16AQ30485555-03981C0E-DA6A-4A56-8498-FBC58245BA3BQ30486428-99309D00-BC17-458D-A8C9-9FA1C6A999ADQ30855603-BA5C1B2C-E377-41A9-8CD1-F7B42BBF4C6FQ33279526-B0365438-1B14-4D79-AF22-00CEFB76E300Q33560404-F384934B-4259-4173-97EA-AB4EF7444780Q33772607-16A23AAB-4928-4D4D-9AC5-9F1B23D21630Q33939662-73E28768-22F5-45A8-89D3-AB492359750FQ34028171-1026DC0D-B213-4679-98A4-D8513924A6AEQ34050681-C5BD449C-057E-43C6-9312-DCABE9BDB17DQ34056329-1DC1B1F7-1B67-4822-A6CC-80538CC6E4DBQ34167593-45DFD769-1038-4387-B6ED-31CB1188C7AEQ34707151-9E087D8D-1F48-4F97-A0B4-E8366DB026A3Q34991616-B841A866-89FC-4189-A9E1-4301F89E23F0Q35017720-893528D8-4F18-4A7E-A8E2-91D2A0B6450AQ35486470-25A87C6F-7A08-4E61-A5EA-995961FEFA65Q35525433-1590FCE9-A882-4060-8339-1A961E673F44Q35579282-DDFF25E7-4DC2-4736-A17D-5C8B7E22A253Q35921510-5B129175-24FB-44A9-A358-6264324E370CQ35969056-2A970C8E-E607-4DE2-A2E3-83DB9794E88CQ36019733-78A811AD-C338-46D2-9735-F0B654392359Q36110203-0D67364E-DC64-4ADC-8133-3861FAA4EB60Q36129863-1A213AC4-E50E-488B-883F-22F1A4EB5719Q36384868-23B370DF-13FB-4E90-AE65-1E7888651DDDQ36408535-6171386D-3B7C-4655-AAC6-2628FC82DEA4Q36661849-1EC8DB28-233D-40F0-9A3B-B92420D01CC5Q36668271-7BC7F2F9-8048-4318-97E2-CF43C05EE802Q36802972-CE2426F6-D5B4-4290-9902-4CC3CA51EC07Q36817612-8779B41E-10A3-4F53-9D19-1988AC776F3DQ36880647-A5DEAB6D-9B89-4C54-B2C0-F640F03AC9DEQ36970179-BBB4E189-C1C3-4D6F-A9E5-39A3D9CCD864Q37039580-03101D48-75B9-4E2E-A529-4074F6580578Q37259798-8AF2F4C6-7BB2-4891-B10C-FD174D5C759FQ37422388-8292C7E9-31FE-4FE7-A516-52F793530665Q37528135-8E38526F-7755-413B-95CC-179E2F7C0F9AQ37762444-58081E60-CA16-4A92-9439-E3C3B82C5345Q37802424-63AFA283-9818-4183-A172-A5662F43A456
P2860
Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Lymphoid cell growth and trans ...... ent of the gene encoding PU.1.
@en
Lymphoid cell growth and trans ...... ent of the gene encoding PU.1.
@nl
type
label
Lymphoid cell growth and trans ...... ent of the gene encoding PU.1.
@en
Lymphoid cell growth and trans ...... ent of the gene encoding PU.1.
@nl
prefLabel
Lymphoid cell growth and trans ...... ent of the gene encoding PU.1.
@en
Lymphoid cell growth and trans ...... ent of the gene encoding PU.1.
@nl
P2093
P50
P356
P1433
P1476
Lymphoid cell growth and trans ...... ent of the gene encoding PU.1.
@en
P2093
Björn Hackanson
Bronwyn M Owens
Christoph Plass
Chunhui Liu
Hiromi Iwasaki
Jeffery L Kutok
Joseph R Tumang
Katharina Wagner
Koichi Akashi
P2888
P356
10.1038/NG1679
P407
P577
2005-11-27T00:00:00Z