Deletion and altered regulation of p16INK4a and p15INK4b in undifferentiated mouse skin tumors.
about
Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signalingAutocrine PDGFR signaling promotes mammary cancer metastasisCellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)Changed genome heterochromatinization upon prolonged activation of the Raf/ERK signaling pathway.MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma.The human oncoprotein MDM2 arrests the cell cycle: elimination of its cell-cycle-inhibitory function induces tumorigenesisThe alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.UV irradiation augments lymphoid malignancies in mice with one functional copy of wild-type p53.A tumor host range selection procedure identifies p150(sal2) as a target of polyoma virus large T antigen.p53 deficiency increases transformation by v-Abl and rescues the ability of a C-terminally truncated v-Abl mutant to induce pre-B lymphoma in vivo.Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescenceGenetic and epigenetic changes in human epithelial cells immortalized by telomerase.Inhibition of MAP kinase kinase causes morphological reversion and dissociation between soft agar growth and in vivo tumorigenesis in angiosarcoma cells.Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by p19Arf/p53 pathway lesions but not p16 Ink4a loss.Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.Loss of heterozygosity and microsatellite instability in hepatocellular carcinoma in Taiwan.Inflammation and Hras signaling control epithelial-mesenchymal transition during skin tumor progression.Evolution of metastasis revealed by mutational landscapes of chemically induced skin cancersEpithelial carcinogenesis in the mouse: correlating the genetics and the biologyIdentification of candidate lung cancer susceptibility genes in mouse using oligonucleotide arrays.MicroRNA (miR)-203 and miR-205 expression patterns identify subgroups of prognosis in cutaneous squamous cell carcinoma.
P2860
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P2860
Deletion and altered regulation of p16INK4a and p15INK4b in undifferentiated mouse skin tumors.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Deletion and altered regulatio ...... ferentiated mouse skin tumors.
@en
Deletion and altered regulatio ...... ferentiated mouse skin tumors.
@nl
type
label
Deletion and altered regulatio ...... ferentiated mouse skin tumors.
@en
Deletion and altered regulatio ...... ferentiated mouse skin tumors.
@nl
prefLabel
Deletion and altered regulatio ...... ferentiated mouse skin tumors.
@en
Deletion and altered regulatio ...... ferentiated mouse skin tumors.
@nl
P2093
P1433
P1476
Deletion and altered regulatio ...... ferentiated mouse skin tumors.
@en
P2093
P304
P407
P50
P577
1995-11-01T00:00:00Z