p53 downregulates expression of the G1/S cell cycle phosphatase Cdc25A.
about
The transcription factor p53: not a repressor, solely an activatorThe p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genesThe role of Cdc25A in the regulation of cell proliferation and apoptosisDual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control.Silencing of protein kinase D2 induces glioma cell senescence via p53-dependent and -independent pathways.CDC25A(Q110del): a novel cell division cycle 25A isoform aberrantly expressed in non-small cell lung cancerUbiquitin proteasomal pathway mediated degradation of p53 in melanomaExpression of p53 target genes in the early phase of long-term potentiation in the rat hippocampal CA1 areaLoss of cyclin-dependent kinase 2 (CDK2) inhibitory phosphorylation in a CDK2AF knock-in mouse causes misregulation of DNA replication and centrosome duplication.The impact of S- and G2-checkpoint response on the fidelity of G1-arrest by cisplatin and its comparison to a non-cross-resistant platinum(IV) analogStimulating effect of normal-dosing of fibrates on cell proliferation: word of warning.Is Cdc25 a druggable target?The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription.One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor.A ceRNA analysis on LMNA gene focusing on the Hutchinson-Gilford progeria syndrome.Prox1 suppresses the proliferation of neuroblastoma cells via a dual action in p27-Kip1 and Cdc25A.p53 activates the PANK1/miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins.Multimodal control of Cdc25A by nitrosative stressMicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response.p53 can repress transcription of cell cycle genes through a p21(WAF1/CIP1)-dependent switch from MMB to DREAM protein complex binding at CHR promoter elements.Cell cycle arrest through indirect transcriptional repression by p53: I have a DREAM.LYG-202 inhibits the proliferation of human colorectal carcinoma HCT-116 cells through induction of G1/S cell cycle arrest and apoptosis via p53 and p21(WAF1/Cip1) expression.
P2860
Q24273295-C66925D8-F382-4BA9-8392-F40B06353211Q28267558-7DA25E12-64FE-4C17-B630-A0224F58285DQ28611420-8DDAF95A-993A-4CD0-AAEC-A42278145108Q33390327-A4914BAD-7440-431B-8414-0FFF87B97459Q33753441-623D1774-A466-41D6-9359-0D39CE7E6D72Q34447183-E8195550-2327-422B-81F8-F2911E74B9C7Q34699448-559FB50E-430C-4890-ACAE-ECCCFEACF5C4Q35124631-8FCD5461-CB5A-417B-9FA9-8A90F1EA8F81Q35867915-0AF0FFDC-BF67-4B80-97E8-85E182D25C89Q36697283-AF1908CD-D469-4854-8CDF-7B39B53D9EA2Q37278876-6D19893E-BFA5-4BD9-B051-003EDEE38C8AQ37347032-9A165949-E459-43A4-9B3B-62D1A393CEB8Q37656480-9FF6F958-D2AB-4405-B0B2-9A5DEABB1474Q37857673-63BD8DEC-97FF-4746-BF3C-51DDC2FC230BQ38492694-598E4360-4521-4A5B-A39D-AEB0B7733680Q39363776-05FCC4ED-ABC5-41D3-8A16-57765756EF85Q39656829-05B20C34-E858-4F62-BDEC-9A0DA7EAFE22Q39939551-3DC0E886-355D-4AAD-8E33-9355F4B4FE4DQ41911349-9FEB78BC-1AA6-41B2-A6E6-2F48858B4D3DQ42260949-C8FC1456-0A79-4D4B-9EB0-BFA1F8D31EF8Q47232697-A2F7FF57-B755-41BC-9F24-36FBBCC5C52FQ53254157-C6948064-1924-412C-9DE8-795F6B658A4F
P2860
p53 downregulates expression of the G1/S cell cycle phosphatase Cdc25A.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
p53 downregulates expression of the G1/S cell cycle phosphatase Cdc25A.
@en
p53 downregulates expression of the G1/S cell cycle phosphatase Cdc25A.
@nl
type
label
p53 downregulates expression of the G1/S cell cycle phosphatase Cdc25A.
@en
p53 downregulates expression of the G1/S cell cycle phosphatase Cdc25A.
@nl
prefLabel
p53 downregulates expression of the G1/S cell cycle phosphatase Cdc25A.
@en
p53 downregulates expression of the G1/S cell cycle phosphatase Cdc25A.
@nl
P2093
P2860
P356
P1433
P1476
p53 downregulates expression of the G1/S cell cycle phosphatase Cdc25A.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1209989
P407
P577
2006-09-25T00:00:00Z
P5875
P6179
1020842066