Securin associates with APCCdh1 in prometaphase but its destruction is delayed by Rae1 and Nup98 until the metaphase/anaphase transition.
about
The function of APC/CCdh1 in cell cycle and beyondBub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesisThe Hippo Pathway Targets Rae1 to Regulate Mitosis and Organ Size and to Feed Back to Regulate Upstream Components Merlin, Hippo, and WartsCyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1).A translational regulator, PUM2, promotes both protein stability and kinase activity of Aurora-ANup98-homeodomain fusions interact with endogenous Nup98 during interphase and localize to kinetochores and chromosome arms during mitosis.Chromosome missegregation causes colon cancer by APC loss of heterozygosity.The nuclear envelope environment and its cancer connections.Identification of novel deregulated RNA metabolism-related genes in non-small cell lung cancer.Nup2 requires a highly divergent partner, NupA, to fulfill functions at nuclear pore complexes and the mitotic chromatin region.Topoisomerase IIα in chromosome instability and personalized cancer therapy.Functional analysis of the NUP98-CCDC28A fusion protein.Targeting karyotypic complexity and chromosomal instability of cancer cells.Expression of Leukemia-Associated Nup98 Fusion Proteins Generates an Aberrant Nuclear Envelope Phenotype.Losing balance: the origin and impact of aneuploidy in cancerNuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy.Rev7/Mad2B plays a critical role in the assembly of a functional mitotic spindle.Whole chromosome instability and cancer: a complex relationshipNuclear pore complex assembly through the cell cycle: regulation and membrane organization.Non-FG mediated transport of the large pre-ribosomal subunit through the nuclear pore complex by the mRNA export factor Gle2Nuclear pore proteins and cancerMulti-layered cancer chromosomal instability phenotype.Boveri revisited: chromosomal instability, aneuploidy and tumorigenesisLearning about cancer from frogs: analysis of mitotic spindles in Xenopus egg extracts.Nuclear transport and the mitotic apparatus: an evolving relationship.APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity.The role of nuclear pore complex in tumor microenvironment and metastasis.Aneuploidy in Cancer and Aging.The roles of the nuclear pore complex in cellular dysfunction, aging and disease.The yin and yang of the Cdkn2a locus in senescence and aging.CAML loss causes anaphase failure and chromosome missegregation.USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation.Nucleoporin Gene Fusions and Hematopoietic Malignancies
P2860
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P2860
Securin associates with APCCdh1 in prometaphase but its destruction is delayed by Rae1 and Nup98 until the metaphase/anaphase transition.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
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2006年學術文章
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name
Securin associates with APCCdh ...... metaphase/anaphase transition.
@en
Securin associates with APCCdh ...... metaphase/anaphase transition.
@nl
type
label
Securin associates with APCCdh ...... metaphase/anaphase transition.
@en
Securin associates with APCCdh ...... metaphase/anaphase transition.
@nl
prefLabel
Securin associates with APCCdh ...... metaphase/anaphase transition.
@en
Securin associates with APCCdh ...... metaphase/anaphase transition.
@nl
P2093
P356
P1433
P1476
Securin associates with APCCdh ...... metaphase/anaphase transition.
@en
P2093
Darren J Baker
Jan M van Deursen
Karthik B Jeganathan
P304
P356
10.4161/CC.5.4.2483
P577
2006-02-15T00:00:00Z