Structure-activity relationships of novel potent MurF inhibitors.

Structure-activity relationships of novel potent MurF inhibitors.

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http://www.wikidata.org/entity/Q53645851
Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closurePhage display-derived inhibitor of the essential cell wall biosynthesis enzyme MurF.An ultraefficient affinity-based high-throughout screening process: application to bacterial cell wall biosynthesis enzyme MurF.A MurF inhibitor that disrupts cell wall biosynthesis in Escherichia coli.Challenges of antibacterial discoveryNovel approach to mapping of resistance mutations in whole genomes by using restriction enzyme modulation of transformation efficiency3,5-dioxopyrazolidines, novel inhibitors of UDP-N- acetylenolpyruvylglucosamine reductase (MurB) with activity against gram-positive bacteriaRole of murF in cell wall biosynthesis: isolation and characterization of a murF conditional mutant of Staphylococcus aureusTreponema pallidum putative novel drug target identification and validation: rethinking syphilis therapeutics with plant-derived terpenoids.Crystallization and preliminary X-ray analysis of a UDP-MurNAc-tripeptide D-alanyl-D-alanine-adding enzyme (PaMurF) from Pseudomonas aeruginosa.Cytoplasmic steps of peptidoglycan biosynthesis.The Gewald multicomponent reaction.Peptidoglycan biosynthesis machinery: a rich source of drug targets.Insight into the structural requirements of thiophene-3-carbonitriles-based MurF inhibitors by 3D-QSAR, molecular docking and molecular dynamics study.MurF inhibitors with antibacterial activity: effect on muropeptide levels.Utility of muropeptide ligase for identification of inhibitors of the cell wall biosynthesis enzyme MurF.A novel assay of bacterial peptidoglycan synthesis for natural product screening.
P2860

Structure-activity relationships of novel potent MurF inhibitors.

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http://www.wikidata.org/entity/Q53645851
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Structure-activity relationships of novel potent MurF inhibitors.
@en
Structure-activity relationships of novel potent MurF inhibitors.
@nl
type
label
Structure-activity relationships of novel potent MurF inhibitors.
@en
Structure-activity relationships of novel potent MurF inhibitors.
@nl
prefLabel
Structure-activity relationships of novel potent MurF inhibitors.
@en
Structure-activity relationships of novel potent MurF inhibitors.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Structure-activity relationships of novel potent MurF inhibitors.
@en
P2093
P304
P31
P356
10.1016/J.BMCL.2003.09.073
P407
P433
P478
P577
P698