Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells.
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Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays.Defect of insulin signal in peripheral tissues: Important role of ceramideCeramides in Alzheimer's Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and Aβ AccumulationThe structural requirements for ceramide activation of serine-threonine protein phosphatasesCeramide dissociates 3'-phosphoinositide production from pleckstrin homology domain translocationAn SH2-domain-containing kinase negatively regulates the phosphatidylinositol-3 kinase pathwayThe effects of obesity on skeletal muscle regenerationp75NTR-dependent modulation of cellular handling of reactive oxygen speciesRole of ceramide in diabetes mellitus: evidence and mechanisms.Cytochrome p450 epoxygenase metabolism of arachidonic acid inhibits apoptosisProtein kinase Akt/PKB phosphorylates heme oxygenase-1 in vitro and in vivo.Roles for dysfunctional sphingolipid metabolism in Alzheimer's disease neuropathogenesis.Differential effects of palmitate and palmitoleate on insulin action and glucose utilization in rat L6 skeletal muscle cells.The therapeutic potential of modulating the ceramide/sphingomyelin pathwayCancer treatment strategies targeting sphingolipid metabolism.Ceramide: second messenger or modulator of membrane structure and dynamics?Ceramides as modulators of cellular and whole-body metabolismAblation of dihydroceramide desaturase 1, a therapeutic target for the treatment of metabolic diseases, simultaneously stimulates anabolic and catabolic signalingSphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism.Ceramide and neurodegeneration: susceptibility of neurons and oligodendrocytes to cell damage and death.Converging roles for sphingolipids and cell stress in the progression of neuro-AIDSLipid profiling of the therapeutic effects of berberine in patients with nonalcoholic fatty liver disease.Natural sphingadienes inhibit Akt-dependent signaling and prevent intestinal tumorigenesis.The twists and turns of sphingolipid pathway in glucose regulationImplication of ceramide, ceramide 1-phosphate and sphingosine 1-phosphate in tumorigenesis.Inhibition of ceramide de novo synthesis with myriocin affects lipid metabolism in the liver of rats with streptozotocin-induced type 1 diabetes.Roles of Diacylglycerols and Ceramides in Hepatic Insulin Resistance.Ceramide in the molecular mechanisms of neuronal cell death. The role of sphingosine-1-phosphate.Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle.SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner.Ceramide metabolism determines glioma cell resistance to chemotherapy.Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism.Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes.Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells.Adiponectin and its Hydrolase-Activated Receptors.Involvement of the Na+/Ca2+ exchanger isoform 1 (NCX1) in neuronal growth factor (NGF)-induced neuronal differentiation through Ca2+-dependent Akt phosphorylation.Interleukin-1beta inhibits ATP-induced protein kinase B activation in renal mesangial cells by two different mechanisms: the involvement of nitric oxide and ceramide.Akt mediates insulin induction of glucose uptake and up-regulation of GLUT4 gene expression in brown adipocytes.Neuronal survival induced by neurotrophins requires calmodulin.Effect of the Alzheimer amyloid fragment Abeta(25-35) on Akt/PKB kinase and survival of PC12 cells.
P2860
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P2860
Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
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2000年學術文章
@zh-hant
name
Inhibition of PKB/Akt1 by C2-c ...... ein phosphatase in PC12 cells.
@en
Inhibition of PKB/Akt1 by C2-c ...... ein phosphatase in PC12 cells.
@nl
type
label
Inhibition of PKB/Akt1 by C2-c ...... ein phosphatase in PC12 cells.
@en
Inhibition of PKB/Akt1 by C2-c ...... ein phosphatase in PC12 cells.
@nl
prefLabel
Inhibition of PKB/Akt1 by C2-c ...... ein phosphatase in PC12 cells.
@en
Inhibition of PKB/Akt1 by C2-c ...... ein phosphatase in PC12 cells.
@nl
P2093
P356
P1476
Inhibition of PKB/Akt1 by C2-c ...... tein phosphatase in PC12 cells
@en
P2093
López-Valdaliso R
P304
P356
10.1006/MCNE.1999.0813
P577
2000-02-01T00:00:00Z