Endosomal sorting and signalling: an emerging role for sorting nexins.
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Sorting nexin 19 regulates the number of dense core vesicles in pancreatic β-cellsMolecular basis for SNX-BAR-mediated assembly of distinct endosomal sorting tubulesStructural basis for different phosphoinositide specificities of the PX domains of sorting nexins regulating G-protein signalingA SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretionStructural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteinsThe E3 ubiquitin ligase Itch regulates sorting nexin 9 through an unconventional substrate recognition domainThe retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi networkA FAM21-containing WASH complex regulates retromer-dependent sortingThe retromer component SNX6 interacts with dynactin p150(Glued) and mediates endosome-to-TGN transportIdentification of SH3 domain interaction partners of human FasL (CD178) by phage display screeningA SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivoA global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transportMembrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5Structure of sorting nexin 11 (SNX11) reveals a novel extended phox homology (PX) domain critical for inhibition of SNX10-induced vacuolationDeficiency of sorting nexin 27 (SNX27) leads to growth retardation and elevated levels of N-methyl-D-aspartate receptor 2C (NR2C)The emerging role of phosphoinositide clustering in intracellular trafficking and signal transductionRole of the Retromer Complex in Neurodegenerative DiseasesPhosphoinositides: tiny lipids with giant impact on cell regulationFunction and regulation of the endosomal fusion and fission machineriesPhosphoinositides in the mammalian endo-lysosomal networkNanoparticle analysis sheds budding insights into genetic drivers of extracellular vesicle biogenesis.Identification of SH3 domain proteins interacting with the cytoplasmic tail of the a disintegrin and metalloprotease 10 (ADAM10)Sorting nexin 6 enhances lamin a synthesis and incorporation into the nuclear envelopeER contact sites define the position and timing of endosome fissionEmerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders.Phosphoinositide binding by the SNX27 FERM domain regulates its localization at the immune synapse of activated T-cells.Mechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPasesStructural Determinants for Binding of Sorting Nexin 17 (SNX17) to the Cytoplasmic Adaptor Protein Krev Interaction Trapped 1 (KRIT1)Functional separation of endosomal fusion factors and the class C core vacuole/endosome tethering (CORVET) complex in endosome biogenesisThe BLOC-1 complex promotes endosomal maturation by recruiting the Rab5 GTPase-activating protein Msb3.Retromer Ensures the Degradation of Autophagic Cargo by Maintaining Lysosome Function in DrosophilaHigh susceptibility to fatty liver disease in two-pore channel 2-deficient miceRetromer is required for apoptotic cell clearance by phagocytic receptor recyclingRegulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7.Recent advances in retromer biologyVPS29 is not an active metallo-phosphatase but is a rigid scaffold required for retromer interaction with accessory proteinsExpression of sorting nexin 18 (SNX18) is dynamically regulated in developing spinal motor neuronsStructure and Membrane Binding Properties of the Endosomal Tetratricopeptide Repeat (TPR) Domain-containing Sorting Nexins SNX20 and SNX21WASH knockout T cells demonstrate defective receptor trafficking, proliferation, and effector function
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Endosomal sorting and signalling: an emerging role for sorting nexins.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Endosomal sorting and signalling: an emerging role for sorting nexins.
@en
Endosomal sorting and signalling: an emerging role for sorting nexins.
@nl
type
label
Endosomal sorting and signalling: an emerging role for sorting nexins.
@en
Endosomal sorting and signalling: an emerging role for sorting nexins.
@nl
prefLabel
Endosomal sorting and signalling: an emerging role for sorting nexins.
@en
Endosomal sorting and signalling: an emerging role for sorting nexins.
@nl
P356
P1476
Endosomal sorting and signalling: an emerging role for sorting nexins.
@en
P2093
Peter J Cullen
P2888
P304
P356
10.1038/NRM2427
P577
2008-06-04T00:00:00Z
P6179
1000993219