Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid (BQCA) as allosteric modulators of the M1 muscarinic receptor.
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Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders.M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory lossMechanistic insights into allosteric structure-function relationships at the M1 muscarinic acetylcholine receptor.Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate ReceptorsMolecular determinants of allosteric modulation at the M1 muscarinic acetylcholine receptor.Recent syntheses of 1,2,3,4-tetrahydroquinolines, 2,3-dihydro-4(1H)-quinolinones and 4(1H)-quinolinones using domino reactions.Prefrontal Cortex-Mediated Impairments in a Genetic Model of NMDA Receptor Hypofunction Are Reversed by the Novel M1 PAM VU6004256.Structure-Activity Relationships of Pan-Gα Coupled Muscarinic Acetylcholine Receptor Positive Allosteric Modulators
P2860
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P2860
Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid (BQCA) as allosteric modulators of the M1 muscarinic receptor.
description
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name
Synthesis and pharmacological ...... of the M1 muscarinic receptor.
@en
Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid
@nl
type
label
Synthesis and pharmacological ...... of the M1 muscarinic receptor.
@en
Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid
@nl
prefLabel
Synthesis and pharmacological ...... of the M1 muscarinic receptor.
@en
Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid
@nl
P50
P356
P1476
Synthesis and pharmacological ...... of the M1 muscarinic receptor
@en
P2093
Ben Capuano
P304
P356
10.1021/JM400540B
P407
P577
2013-06-17T00:00:00Z