about
The miR-17-92 cluster of microRNAs confers tumorigenicity by inhibiting oncogene-induced senescencep38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanismsThe HBP1 transcriptional repressor participates in RAS-induced premature senescenceThe Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cellsStem cells, senescence, neosis and self-renewal in cancer.p19ras brings a new twist to the regulation of p73 by Mdm2Registered report: senescence surveillance of pre-malignant hepatocytes limits liver cancer developmentThe senescence-associated secretory phenotype: the dark side of tumor suppressionGranule exocytosis mediates immune surveillance of senescent cells.Role of senescence and mitotic catastrophe in cancer therapy.Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescenceProteasomal and genetic inactivation of the NF1 tumor suppressor in gliomagenesis.TAp63 induces senescence and suppresses tumorigenesis in vivo.Activation of Bmp2-Smad1 signal and its regulation by coordinated alteration of H3K27 trimethylation in Ras-induced senescence.Fat tissue, aging, and cellular senescence.Hypoxia, melanocytes and melanoma - survival and tumor development in the permissive microenvironment of the skin.miR-22 represses cancer progression by inducing cellular senescenceNuclear size, nuclear pore number and cell cycle.Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression.Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancerp63-microRNA feedback in keratinocyte senescence.Implications of cellular senescence in tissue damage response, tumor suppression, and stem cell biology.The specific role of pRb in p16 (INK4A) -mediated arrest of normal and malignant human breast cellsRegulation of senescence by microRNA biogenesis factorsVisualizing the dynamics of p21(Waf1/Cip1) cyclin-dependent kinase inhibitor expression in living animals.Human Mut T Homolog 1 (MTH1): a roadblock for the tumor-suppressive effects of oncogenic RAS-induced ROS.SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer.MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors.NKG2D ligands mediate immunosurveillance of senescent cells.SWI/SNF mediates polycomb eviction and epigenetic reprogramming of the INK4b-ARF-INK4a locusTelomerase as a useful target in cancer fighting-the breast cancer case.Mechanisms controlling cell cycle exit upon terminal differentiationMolecular pathogenesis and progression of prostate cancerConserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence.The in situ local immune response, tumour senescence and proliferation in colorectal cancer.Induction of p38δ expression plays an essential role in oncogenic ras-induced senescenceInflammatory signaling and cellular senescenceHeparan sulfation is essential for the prevention of cellular senescence.Telomeres, histone code, and DNA damage response.Regulation of gene expression and cellular proliferation by histone H2A.Z.
P2860
Q24617045-327A1E20-7142-4888-83C2-1D6293F80389Q24657888-E12582D1-FBF6-4C36-9C39-408701C0A869Q24672298-A54EAEA6-5050-4207-A347-89DD16EAF99CQ24680814-E5A07DE9-D256-4003-9FD2-0A9776E1ACCBQ27497212-58CAFD38-0643-46FF-948E-1A7AF6B262CCQ28243153-26E29FE7-CAFA-4117-AA1E-C3568F3D9623Q28650504-E7BAAE6F-87C5-4C6E-A3DF-9F320A11122EQ29620106-04477C07-A03F-4290-BBC8-E8F6B50D0989Q30538996-6BB9DB5D-1F61-4F23-A5D4-60BC83DED3CBQ33683160-3349E5A5-B2FD-4FD5-985C-CD152C25E1D8Q33929054-92FA7B2B-123D-4DAF-AA26-DF29FA23A4CDQ33962607-66D214E4-B508-464B-8E48-2C8F7251D1FFQ34060915-CDED45CA-66E3-4B75-8690-4DBEE1700B55Q34071417-596242AB-C552-4FB6-A612-ADB619A914CCQ34130783-5B0CBE0D-060E-49AB-98C4-46A836E0C6BEQ34570988-0E8B848E-7A44-40D0-9871-18C6A69AF973Q34825182-99C1358A-17C2-4698-808D-A77EEECB5301Q35079147-26985A46-48A3-48E5-88B0-DE440C52F0B5Q35223274-925D9178-90F3-445D-994A-8BC2F33174B5Q35645149-185136EF-1AA9-40D9-B04E-01914D749999Q35709311-E91D84A2-B46E-4C4C-ADAB-43DF388ECE87Q35773743-5E9CBD7D-032A-4116-A036-C47C19FBA56CQ35881972-BE934071-BC76-497E-9916-DD67A945E73BQ35948994-B632AED4-FB9A-46E1-90F6-4BE23C719B7AQ35989505-F63B52F7-7D7B-4782-8F02-C3E5CB871D6CQ36129977-659D2CD3-B0A7-4F03-A419-2F92B7C6E111Q36163245-1F36D628-4BD6-4988-A36B-D6161E507568Q36497139-91E866E9-D553-4B60-ADA3-2240CBD95B18Q36681455-5A79A0BF-650C-4804-86A7-58243DF26552Q36710858-5984FB57-CED7-4A48-8863-F2E7F8D31BB3Q36868580-A51FC328-8C03-4022-B31B-F94A58E7716AQ37012736-C1A1CEEE-486B-495A-8014-9949752A1B1CQ37055715-1B320BE9-ED08-4D68-AFA6-FA8DC6080D16Q37133206-38E70CF9-830F-4FD4-ACF8-734FABEB0675Q37235543-0439C55E-11DF-4B87-83B2-EF07C84741D3Q37264977-FD3FDB09-93A7-464C-B654-89561BE264F1Q37320836-FB8FB902-80C0-46A7-A7F0-1FF3154F9604Q37353998-6D30CBB9-727D-41B5-9A95-EED512578367Q37384129-4310C29F-1743-426A-BA42-D0C521702AB7Q37398628-0EBF7F6B-9F09-4DCD-8E8E-F9E721D5BFCA
P2860
description
im September 2005 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована у вересні 2005
@uk
name
Senescence comes of age
@en
Senescence comes of age
@nl
type
label
Senescence comes of age
@en
Senescence comes of age
@nl
prefLabel
Senescence comes of age
@en
Senescence comes of age
@nl
P2860
P356
P1433
P1476
Senescence comes of age
@en
P2093
Scott W Lowe
P2860
P2888
P304
P356
10.1038/NM0905-920
P407
P577
2005-09-01T00:00:00Z
P6179
1038451220