Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation
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Hematopoietic stem cell development, niches, and signaling pathwaysSoluble frizzled-related protein 1 is estrogen inducible in bone marrow stromal cells and suppresses the earliest events in lymphopoiesisPh+/VE-cadherin+ identifies a stem cell like population of acute lymphoblastic leukemia sustained by bone marrow niche cellsWnt signaling promotes hematoendothelial cell development from human embryonic stem cellsWnt signaling: the good and the badKlotho and agingHematopoietic fingerprints: an expression database of stem cells and their progenyHematopoietic stem cell niche maintenance during homeostasis and regenerationWnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia developmentGenetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regenerationLEF-1 is a decisive transcription factor in neutrophil granulopoiesisChallenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?A critical role for Apc in hematopoietic stem and progenitor cell survivalHematopoietic stem cell: self-renewal versus differentiationHematopoiesis: an evolving paradigm for stem cell biologyActivation of Wnt/β-catenin protein signaling induces mitochondria-mediated apoptosis in hematopoietic progenitor cellsBeta-catenin (CTNNB1) promotes preovulatory follicular development but represses LH-mediated ovulation and luteinization.Hedgehog and Wingless stabilize but do not induce cell fate during Drosophila dorsal embryonic epidermal patterning.Perturbation of single hematopoietic stem cell fates in artificial nichesDKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration.MicroRNA-29 induces cellular senescence in aging muscle through multiple signaling pathwaysLoss of β-catenin triggers oxidative stress and impairs hematopoietic regeneration.Angelica Sinensis Polysaccharide Prevents Hematopoietic Stem Cells Senescence in D-Galactose-Induced Aging Mouse Model.Integrated genetic approaches identify the molecular mechanisms of Sox4 in early B-cell development: intricate roles for RAG1/2 and CK1ε.The Apc(min) mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS.Wnt/β-catenin signaling induces the aging of mesenchymal stem cells through the DNA damage response and the p53/p21 pathway.Sonic hedgehog acts as a negative regulator of {beta}-catenin signaling in the adult tongue epithelium.Histone deacetylase inhibition enhances self renewal and cardioprotection by human cord blood-derived CD34 cells.beta-Catenin expression in the bone marrow microenvironment is required for long-term maintenance of primitive hematopoietic cells.Sulfatase modifying factor 1-mediated fibroblast growth factor signaling primes hematopoietic multilineage development.Effects of regulator of G protein signaling 19 (RGS19) on heart development and functionmTOR mediates Wnt-induced epidermal stem cell exhaustion and aging.Dysregulation of Frizzled 6 is a critical component of B-cell leukemogenesis in a mouse model of chronic lymphocytic leukemia.Signalling pathways that control vertebrate haematopoietic stem cell specification.WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.Wnt-related molecules and signaling pathway equilibrium in hematopoiesis.Indirect effects of Wnt3a/β-catenin signalling support mouse spermatogonial stem cells in vitro.Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo.Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS.Heterogeneous sensitivity of human acute myeloid leukemia to β-catenin down-modulation.
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Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation
description
im September 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 03 September 2006
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована у вересні 2006
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name
Hematopoietic stem cell and mu ...... stitutive β-catenin activation
@en
Hematopoietic stem cell and mu ...... stitutive β-catenin activation
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type
label
Hematopoietic stem cell and mu ...... stitutive β-catenin activation
@en
Hematopoietic stem cell and mu ...... stitutive β-catenin activation
@nl
prefLabel
Hematopoietic stem cell and mu ...... stitutive β-catenin activation
@en
Hematopoietic stem cell and mu ...... stitutive β-catenin activation
@nl
P2093
P2860
P50
P356
P1433
P1476
Hematopoietic stem cell and mu ...... tutive beta-catenin activation
@en
P2093
Joerg Huelsken
Makoto M Taketo
Marina Scheller
Walter Birchmeier
P2860
P304
P356
10.1038/NI1387
P407
P577
2006-09-03T00:00:00Z