Intraclonal diversification of immunoglobulin light chains in a subset of chronic lymphocytic leukemia alludes to antigen-driven clonal evolution
about
Molecular and cytogenetic characterization of expanded B-cell clones from multiclonal versus monoclonal B-cell chronic lymphoproliferative disordersMutation pattern of paired immunoglobulin heavy and light variable domains in chronic lymphocytic leukemia B cellsDistinct gene expression profiles in subsets of chronic lymphocytic leukemia expressing stereotyped IGHV4-34 B-cell receptors.Silenced B-cell receptor response to autoantigen in a poor-prognostic subset of chronic lymphocytic leukemia.Intraclonal cell expansion and selection driven by B cell receptor in chronic lymphocytic leukemia.An entity evolving into a community: defining the common ancestor and evolutionary trajectory of chronic lymphocytic leukemia stereotyped subset #4.Distinct transcriptional control in major immunogenetic subsets of chronic lymphocytic leukemia exhibiting subset-biased global DNA methylation profiles.Autoantigen can promote progression to a more aggressive TCL1 leukemia by selecting variants with enhanced B-cell receptor signalingTemporal dynamics of clonal evolution in chronic lymphocytic leukemia with stereotyped IGHV4-34/IGKV2-30 antigen receptors: longitudinal immunogenetic evidence.Splenic marginal-zone lymphoma: ontogeny and genetics.Antigen receptor stereotypy in chronic lymphocytic leukemia.Pathogen-specific B-cell receptors drive chronic lymphocytic leukemia by light-chain-dependent cross-reaction with autoantigens.Immunoglobulin gene repertoire diversification and selection in the stomach - from gastritis to gastric lymphomas.Immunoglobulin gene repertoire in chronic lymphocytic leukemia: insight into antigen selection and microenvironmental interactions.Systemic amyloidosis associated with chronic lymphocytic leukemia/small lymphocytic lymphoma.Immunoglobulin gene repertoire in ocular adnexal lymphomas: hints on the nature of the antigenic stimulation.Restrictions in the T-cell repertoire of chronic lymphocytic leukemia: high-throughput immunoprofiling supports selection by shared antigenic elements.B Cell Anergy Modulated by TLR1/2 and the miR-17∼92 Cluster Underlies the Indolent Clinical Course of Chronic Lymphocytic Leukemia Stereotyped Subset #4.
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Intraclonal diversification of immunoglobulin light chains in a subset of chronic lymphocytic leukemia alludes to antigen-driven clonal evolution
description
im Mai 2010 veröffentlichter wissenschaftlicher Artikel
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scientific article published on 13 May 2010
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wetenschappelijk artikel
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наукова стаття, опублікована в травні 2010
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name
Intraclonal diversification of ...... ntigen-driven clonal evolution
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Intraclonal diversification of ...... ntigen-driven clonal evolution
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type
label
Intraclonal diversification of ...... ntigen-driven clonal evolution
@en
Intraclonal diversification of ...... ntigen-driven clonal evolution
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prefLabel
Intraclonal diversification of ...... ntigen-driven clonal evolution
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Intraclonal diversification of ...... ntigen-driven clonal evolution
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Intraclonal diversification of ...... ntigen-driven clonal evolution
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A Hadzidimitriou
A Kouvatsi
A Tsaftaris
K Stamatopoulos
L-A Sutton
N Darzentas
R Rosenquist
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10.1038/LEU.2010.90
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2010-05-13T00:00:00Z