Stimulation through the T Cell Receptor Induces Cbl Association with Crk Proteins and the Guanine Nucleotide Exchange Protein C3G
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Functional association between SLAP-130 and SLP-76 in Jurkat T cellsThe role of a lymphoid-restricted, Grb2-like SH3-SH2-SH3 protein in T cell receptor signalingEpstein-Barr virus latent membrane protein 2A (LMP2A) employs the SLP-65 signaling moduleGrpL, a Grb2-related adaptor protein, interacts with SLP-76 to regulate nuclear factor of activated T cell activationThe Role of Crk Adaptor Proteins in T-Cell Adhesion and MigrationThe adaptor protein Crk in immune responseRegulation of Cbl molecular interactions by the co-receptor molecule CD43 in human T cellsThe involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activationRegulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptorLAT, the linker for activation of T cells: a bridge between T cell-specific and general signaling pathwaysDifferential signaling after beta1 integrin ligation is mediated through binding of CRKL to p120(CBL) and p110(HEF1)Characterization of Lnk. An adaptor protein expressed in lymphocytesThe type I interferon receptor mediates tyrosine phosphorylation of the CrkL adaptor proteinInterleukin-2 stimulation induces tyrosine phosphorylation of p120-Cbl and CrkL and formation of multimolecular signaling complexes in T lymphocytes and natural killer cellsCoordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinasesThe CBL-related protein CBLB participates in FLT3 and interleukin-7 receptor signal transduction in pro-B cellsPhosphorylation of CrkII adaptor protein at tyrosine 221 by epidermal growth factor receptorA novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cellsCbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323B cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteinsSteel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL)Myosin IIA modulates T cell receptor transport and CasL phosphorylation during early immunological synapse formationFyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cellsC3G forms complexes with Bcr-Abl and p38α MAPK at the focal adhesions in chronic myeloid leukemia cells: implication in the regulation of leukemic cell adhesion.Signalling to actin: role of C3G, a multitasking guanine-nucleotide-exchange factor.TULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitin.T cell activation induces direct binding of the Crk adapter protein to the regulatory subunit of phosphatidylinositol 3-kinase (p85) via a complex mechanism involving the Cbl protein.Engagement of the CrkL adapter in interleukin-5 signaling in eosinophils.The adapter protein Crkl links Cbl to C3G after integrin ligation and enhances cell migration.CrkL mediates Ras-dependent activation of the Raf/ERK pathway through the guanine nucleotide exchange factor C3G in hematopoietic cells stimulated with erythropoietin or interleukin-3.T cell activation stimulates the association of enzymatically active tyrosine-phosphorylated ZAP-70 with the Crk adapter proteins.The functional role of CrkII in actin cytoskeleton organization and mitogenesis.Activation of a CrkL-stat5 signaling complex by type I interferons.Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex.Downstream of Crk adaptor signaling pathway: activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G.Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins.Cbl suppresses B cell receptor-mediated phospholipase C (PLC)-gamma2 activation by regulating B cell linker protein-PLC-gamma2 binding.Beyond the RING: CBL proteins as multivalent adapters.A PKC-SHP1 signaling axis desensitizes Fcγ receptor signaling by reducing the tyrosine phosphorylation of CBL and regulates FcγR mediated phagocytosis.WIP regulates signaling via the high affinity receptor for immunoglobulin E in mast cells.
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P2860
Stimulation through the T Cell Receptor Induces Cbl Association with Crk Proteins and the Guanine Nucleotide Exchange Protein C3G
description
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
im April 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Journal of Biological Chemistry
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована у квітні 1996
@uk
name
Stimulation through the T Cell ...... ucleotide Exchange Protein C3G
@en
Stimulation through the T Cell ...... ucleotide Exchange Protein C3G
@nl
type
label
Stimulation through the T Cell ...... ucleotide Exchange Protein C3G
@en
Stimulation through the T Cell ...... ucleotide Exchange Protein C3G
@nl
prefLabel
Stimulation through the T Cell ...... ucleotide Exchange Protein C3G
@en
Stimulation through the T Cell ...... ucleotide Exchange Protein C3G
@nl
P2093
P2860
P356
P1476
Stimulation through the T Cell ...... ucleotide Exchange Protein C3G
@en
P2093
Brian J. Druker
Govindaswamy Panchamoorthy
Hamid Band
Kris A. Reedquist
Steven E. Shoelson
Toru Fukazawa
Wallace Y. Langdon
P2860
P304
P356
10.1074/JBC.271.14.8435
P407
P577
1996-04-05T00:00:00Z