Differences in Activity between α and β Type I Interferons Explored by Mutational Analysis
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IFN-beta induces serine phosphorylation of Stat-1 in Ewing's sarcoma cells and mediates apoptosis via induction of IRF-1 and activation of caspase-7Glycoengineering of interferon-β 1a improves its biophysical and pharmacokinetic propertiesCatalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinaseTherapeutic alpha-interferons protein: structure, production, and biosimilar.IFN-zeta/ limitin: a member of type I IFN with mild lympho-myelosuppression.Selective Blockade of Interferon-α and -β Reveals Their Non-Redundant Functions in a Mouse Model of West Nile Virus InfectionThe Role of Latently Infected B Cells in CNS Autoimmunity.The role of TRAF2 binding to the type I interferon receptor in alternative NF kappaB activation and antiviral responseThe interferons and their receptors--distribution and regulation.Comparative analysis of IRF and IFN-alpha expression in human plasmacytoid and monocyte-derived dendritic cells.Characterization of N-terminal interferon tau mutants: P26L affords enhanced activity and lack of toxicity.Strong inhibition of Ewing tumor xenograft growth by combination of human interferon-alpha or interferon-beta with ifosfamide.Dimerization of the interferon type I receptor IFNaR2-2 is sufficient for induction of interferon effector genes but not for full antiviral activity.USP18 establishes the transcriptional and anti-proliferative interferon α/β differential
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P2860
Differences in Activity between α and β Type I Interferons Explored by Mutational Analysis
description
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
im April 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Journal of Biological Chemistry
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована у квітні 1998
@uk
name
Differences in Activity betwee ...... xplored by Mutational Analysis
@en
Differences in Activity betwee ...... xplored by Mutational Analysis
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type
label
Differences in Activity betwee ...... xplored by Mutational Analysis
@en
Differences in Activity betwee ...... xplored by Mutational Analysis
@nl
prefLabel
Differences in Activity betwee ...... xplored by Mutational Analysis
@en
Differences in Activity betwee ...... xplored by Mutational Analysis
@nl
P2093
P2860
P50
P356
P1476
Differences in activity betwee ...... xplored by mutational analysis
@en
P2093
D Monneron
K Mogensen
M Lewerenz
P2860
P304
P356
10.1074/JBC.273.14.8003
P407
P577
1998-04-01T00:00:00Z