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Fexinidazole--a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sicknessVirology, Epidemiology and Pathology of Glossina Hytrosavirus, and Its Control Prospects in Laboratory Colonies of the Tsetse Fly, Glossina pallidipes (Diptera; Glossinidae)Management of trypanosomiasis and leishmaniasisBromopyrrole alkaloids as lead compounds against protozoan parasitesRegulation of RNA binding proteins in trypanosomatid protozoan parasitesThe role of cytokines in the pathogenesis and staging of Trypanosoma brucei rhodesiense sleeping sicknessWho Neglects Neglected Tropical Diseases? - Korean PerspectiveOverview of the Diagnostic Methods Used in the Field for Human African Trypanosomiasis: What Could Change in the Next Years?The ever unfolding story of cAMP signaling in trypanosomatids: vive la difference!A current analysis of chemotherapy strategies for the treatment of human African trypanosomiasisPersistent digestive disorders in the tropics: causative infectious pathogens and reference diagnostic testsTrypanocidal activity of marine natural productsRecent developments in drug discovery for leishmaniasis and human African trypanosomiasisEpidemiology of human African trypanosomiasisIn vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasisThree-dimensional structure of the Trypanosome flagellum suggests that the paraflagellar rod functions as a biomechanical springImplications of Heterogeneous Biting Exposure and Animal Hosts on Trypanosomiasis brucei gambiense Transmission and ControlThe Trypanosoma brucei Life Cycle Switch TbPTP1 Is Structurally Conserved and Dephosphorylates the Nucleolar Protein NOPP44/46Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational SelectionStructures of Trypanosoma brucei methionyl-tRNA synthetase with urea-based inhibitors provide guidance for drug design against sleeping sicknessStructure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 15-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase InhibitorsA targeted door-to-door strategy for sleeping sickness detection in low-prevalence settings in Côte d’IvoireAntiparasitic therapyNECT is next: implementing the new drug combination therapy for Trypanosoma brucei gambiense sleeping sicknessA molecular mechanism for eflornithine resistance in African trypanosomesIsolation of Trypanosoma brucei gambiense from cured and relapsed sleeping sickness patients and adaptation to laboratory miceUntargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against Trypanosoma bruceiIsothermal microcalorimetry, a new tool to monitor drug action against Trypanosoma brucei and Plasmodium falciparumNaphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanismPyrimidine biosynthesis is not an essential function for Trypanosoma brucei bloodstream formsSafety, pharmacokinetic, and efficacy studies of oral DB868 in a first stage vervet monkey model of human African trypanosomiasisAquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprolHandling uncertainty in dynamic models: the pentose phosphate pathway in Trypanosoma bruceiAn Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma bruceiTrypanothione reductase: a target protein for a combined in vitro and in silico screening approachGenome-Wide Comparative Analysis of Chemosensory Gene Families in Five Tsetse Fly SpeciesDiscovery of Infection Associated Metabolic Markers in Human African TrypanosomiasisGenomic and Proteomic Studies on the Mode of Action of Oxaboroles against the African TrypanosomeTrypanosoma brucei gambiense Infections in Mice Lead to Tropism to the Reproductive Organs, and Horizontal and Vertical Transmission
P2860
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P2860
description
article publié dans la revue scientifique The Lancet
@fr
im Januar 2010 veröffentlichter wissenschaftlicher Artikel
@de
наукова стаття, опублікована в січні 2010
@uk
ശാസ്ത്രപ്രബന്ധം
@ml
name
Human African trypanosomiasis
@en
type
label
Human African trypanosomiasis
@en
prefLabel
Human African trypanosomiasis
@en
P2093
P1433
P1476
Human African trypanosomiasis
@en
P2093
Christian Burri
Francois Chappuis
Johannes Blum
P304
P407
P577
2010-01-09T00:00:00Z