Proteolytic inactivation of ADAMTS13 by thrombin and plasmin.
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ADAMTS13 substrate recognition of von Willebrand factor A2 domainPathophysiology of thrombotic thrombocytopenic purpuraCurrent concepts in thrombotic thrombocytopenic purpuraPathogenesis of thrombotic microangiopathiesAllosteric activation of ADAMTS13 by von Willebrand factor.Further characterization of ADAMTS-13 inactivation by thrombin.The role of ADAMTS13 in the new pathogenesis of TTP.Molecular biology of ADAMTS13 and diagnostic utility of ADAMTS13 proteolytic activity and inhibitor assays.A rapid enzyme-linked assay for ADAMTS-13.Systemic antithrombotic effects of ADAMTS13.Insights into von Willebrand factor proteolysis: clinical implications.A new tool to further explore the role of ADAMTS-13 in health and disease.Plasma fibrinogen gamma' chain content in the thrombotic microangiopathy syndrome.ADAMTS13 and microvascular thrombosisThrombotic microangiopathies: an update.The clinical utility of ADAMTS13 activity, antigen and autoantibody assays in thrombotic thrombocytopenic purpura.Thrombotic thrombocytopenic purpura: a thrombotic disorder caused by ADAMTS13 deficiencyADAMTS13 activity and the presence of acquired inhibitors in human immunodeficiency virus-related thrombotic thrombocytopenic purpura.Degradation of circulating von Willebrand factor and its regulator ADAMTS13 implicates secreted Bacillus anthracis metalloproteases in anthrax consumptive coagulopathy.The kidney in thrombotic thrombocytopenic purpura.An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF[Thrombotic microangiopathy after extracorporeal circulation: important differential diagnosis].Plasma exchange therapy for thrombotic microangiopathies.Severe dengue is associated with consumption of von Willebrand factor and its cleaving enzyme ADAMTS-13VWF excess and ADAMTS13 deficiency: a unifying pathomechanism linking inflammation to thrombosis in DIC, malaria, and TTP.Conformational activation of ADAMTS13.Severe Plasmodium falciparum malaria is associated with circulating ultra-large von Willebrand multimers and ADAMTS13 inhibitionThrombocytopenia-Associated Multiple Organ Failure and Acute Kidney Injury.A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malariaADAMTS13 and anti-ADAMTS13 autoantibodies in thrombotic thrombocytopenic purpura - current perspectives and new treatment strategies.A model for the conformational activation of the structurally quiescent metalloprotease ADAMTS13 by von Willebrand factor.The prognostic value of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13) deficiency in septic shock patients involves interleukin-6 and is not dependent on disseminated intravascular coagulationUnraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.Thrombin-dependent MMP-2 activity is regulated by heparan sulfate.Why Do We Need ADAMTS13?Mechanism of von Willebrand factor scissile bond cleavage by a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13).Hypochlorous acid generated by neutrophils inactivates ADAMTS13: an oxidative mechanism for regulating ADAMTS13 proteolytic activity during inflammation.The role of the ADAMTS13 cysteine-rich domain in VWF binding and proteolysis.Increased prothrombotic property as a risk factor of acute kidney injury after surgical repair of abdominal aortic aneurysm: a prospective observational study.Modulation of the von Willebrand factor-dependent platelet adhesion through alternative proteolytic pathways
P2860
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P2860
Proteolytic inactivation of ADAMTS13 by thrombin and plasmin.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Proteolytic inactivation of ADAMTS13 by thrombin and plasmin.
@en
Proteolytic inactivation of ADAMTS13 by thrombin and plasmin.
@nl
type
label
Proteolytic inactivation of ADAMTS13 by thrombin and plasmin.
@en
Proteolytic inactivation of ADAMTS13 by thrombin and plasmin.
@nl
prefLabel
Proteolytic inactivation of ADAMTS13 by thrombin and plasmin.
@en
Proteolytic inactivation of ADAMTS13 by thrombin and plasmin.
@nl
P2093
P1433
P1476
Proteolytic inactivation of ADAMTS13 by thrombin and plasmin
@en
P2093
David A Lane
James B Rance
Jonathan K Lam
Luigina R Mollica
P304
P356
10.1182/BLOOD-2004-03-1101
P407
P577
2004-09-23T00:00:00Z