PR48, a novel regulatory subunit of protein phosphatase 2A, interacts with Cdc6 and modulates DNA replication in human cells
about
The metabolic advantage of tumor cellsChromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosisProtein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signallingB55alpha PP2A holoenzymes modulate the phosphorylation status of the retinoblastoma-related protein p107 and its activationProtein phosphatase 2A is targeted to cell division control protein 6 by a calcium-binding regulatory subunitThe Human Pseudoautosomal Region (PAR): Origin, Function and FuturePP2A: more than a reset switch to activate pRB proteins during the cell cycle and in response to signaling cues.Structure of the Ca2+-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylationStructural and biochemical characterization of human PR70 in isolation and in complex with the scaffolding subunit of protein phosphatase 2AProtein phosphatase 2A holoenzyme assembly: identification of contacts between B-family regulatory and scaffolding A subunitsAlterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the A beta subunit geneA developmentally regulated, neuron-specific splice variant of the variable subunit Bbeta targets protein phosphatase 2A to mitochondria and modulates apoptosisDiversity in genomic organisation, developmental regulation and distribution of the murine PR72/B" subunits of protein phosphatase 2AATM-dependent dissociation of B55 regulatory subunit from nuclear PP2A in response to ionizing radiation.PP2A regulatory subunit Bα controls endothelial contractility and vessel lumen integrity via regulation of HDAC7.Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex.X chromosome-linked CNVs in male infertility: discovery of overall duplication load and recurrent, patient-specific gains with potential clinical relevance.Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer.The role of adenovirus E4orf4 protein in viral replication and cell killing.A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins.Mutation of cyclin/cdk phosphorylation sites in HsCdc6 disrupts a late step in initiation of DNA replication in human cellsRegulation of the final stage of mitosis by components of the pre-replicative complex and a polo kinase.The role of serine/threonine protein phosphatases in exocytosisIdentification of the first PAR1 deletion encompassing upstream SHOX enhancers in a family with idiopathic short stature.The B''/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A.Protein phosphatase 2A subunit PR70 interacts with pRb and mediates its dephosphorylationQuantitative proteomics reveals novel protein interaction partners of PP2A catalytic subunit in pancreatic β-cellsB56-associated protein phosphatase 2A is required for survival and protects from apoptosis in Drosophila melanogaster.The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene.Protein phosphatase 2A regulatory subunit Bbeta promotes MAP kinase-mediated migration of A431 cells.Toxicity of human adenovirus E4orf4 protein in Saccharomyces cerevisiae results from interactions with the Cdc55 regulatory B subunit of PP2A.Crosstalk and competition in signaling networksProtein phosphorylation and protein phosphatases. De Panne, Belgium, September 19-24, 1999.Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation.Modeling abnormal early development with induced pluripotent stem cells from aneuploid syndromes.Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene.The B″ regulatory subunit of protein phosphatase 2A mediates the dephosphorylation of rice retinoblastoma-related protein-1.Inhibition of cell proliferation by nobiletin, a dietary phytochemical, associated with apoptosis and characteristic gene expression, but lack of effect on early rat hepatocarcinogenesis in vivo.Molecular characterisation of a case of dicentric Y presented as nonobstructive azoospermia with testicular early maturation arrest.The Arabidopsis TONNEAU2 gene encodes a putative novel protein phosphatase 2A regulatory subunit essential for the control of the cortical cytoskeleton.
P2860
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P2860
PR48, a novel regulatory subunit of protein phosphatase 2A, interacts with Cdc6 and modulates DNA replication in human cells
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2000 nî lūn-bûn
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2000年の論文
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PR48, a novel regulatory subun ...... DNA replication in human cells
@ast
PR48, a novel regulatory subun ...... DNA replication in human cells
@en
PR48, a novel regulatory subun ...... DNA replication in human cells
@en-gb
PR48, a novel regulatory subun ...... DNA replication in human cells
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PR48, a novel regulatory subun ...... DNA replication in human cells
@ast
PR48, a novel regulatory subun ...... DNA replication in human cells
@en
PR48, a novel regulatory subun ...... DNA replication in human cells
@en-gb
PR48, a novel regulatory subun ...... DNA replication in human cells
@nl
prefLabel
PR48, a novel regulatory subun ...... DNA replication in human cells
@ast
PR48, a novel regulatory subun ...... DNA replication in human cells
@en
PR48, a novel regulatory subun ...... DNA replication in human cells
@en-gb
PR48, a novel regulatory subun ...... DNA replication in human cells
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P2093
P2860
P1476
PR48, a novel regulatory subun ...... DNA replication in human cells
@en
P2093
P2860
P304
P356
10.1128/MCB.20.3.1021-1029.2000
P407
P577
2000-02-01T00:00:00Z