Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization - Test2 - elhamkhani - TriplyDB

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

http://www.wikidata.org/entity/Q24533531

about

PR48, a novel regulatory subunit of protein phosphatase 2A, interacts with Cdc6 and modulates DNA replication in human cells DNA replication at the single-molecule level SET-related cell division autoantigen-1 (CDA1) arrests cell growth CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair The regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cells Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis Regulation of CDC6, geminin, and CDT1 in human cells that undergo polyploidization Reversal of growth suppression by p107 via direct phosphorylation by cyclin D1/cyclin-dependent kinase 4 Human cytomegalovirus infection leads to accumulation of geminin and inhibition of the licensing of cellular DNA replication.Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycle Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase Human geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1 E2F7, a novel E2F featuring DP-independent repression of a subset of E2F-regulated genes Protein phosphatase 2A is targeted to cell division control protein 6 by a calcium-binding regulatory subunit Replication licensing and cancer--a fatal entanglement?Preventing re-replication of chromosomal DNA.Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6 Cdc7-Dbf4 and the human S checkpoint response to UVC Loss of Geminin induces rereplication in the presence of functional p53 Selective instability of Orc1 protein accounts for the absence of functional origin recognition complexes during the M-G(1) transition in mammals The Non-Canonical Role of Aurora-A in DNA Replication Targeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitors Genomic instability in cancer.Spatio-temporal regulation of the human licensing factor Cdc6 in replication and mitosis.Orc1 Binding to Mitotic Chromosomes Precedes Spatial Patterning during G1 Phase and Assembly of the Origin Recognition Complex in Human Cells.Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus.Regulation of Plasmodium falciparum Origin Recognition Complex subunit 1 (PfORC1) function through phosphorylation mediated by CDK-like kinase PK5 Regulation and Function of Cdt1; A Key Factor in Cell Proliferation and Genome Stability Inhibition of Mcm4,6,7 helicase activity by phosphorylation with cyclin A/Cdk2 Subsets of human origin recognition complex (ORC) subunits are expressed in non-proliferating cells and associate with non-ORC proteins Phosphorylation of the CCAAT displacement protein (CDP)/Cux transcription factor by cyclin A-Cdk1 modulates its DNA binding activity in G(2)Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms Nuclear organization of DNA replication initiation proteins in mammalian cells Cyclin-dependent kinases phosphorylate human Cdt1 and induce its degradation CDC6: from DNA replication to cell cycle checkpoints and oncogenesis Cellular checkpoint mechanisms monitoring proper initiation of DNA replication

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Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

http://www.wikidata.org/entity/Q24533531

description

1999 nî lūn-bûn

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1999 թուականի Յունուարին հրատարակուած գիտական յօդուած

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1999 թվականի հունվարին հրատարակված գիտական հոդված

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1999年の論文

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1999年学术文章

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1999年学术文章

@zh-cn

1999年学术文章

@zh-hans

1999年学术文章

@zh-my

1999年学术文章

@zh-sg

1999年學術文章

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name

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

@ast

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

@en

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

@en-gb

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

@nl

type

label

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

@ast

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

@en

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

@en-gb

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

@nl

prefLabel

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

@ast

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

@en

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

@en-gb

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

@nl

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The EMBO Journal

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Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

@en

P2093

B O Petersen

http://www.w3.org/2001/XMLSchema#string

C S Sørensen

http://www.w3.org/2001/XMLSchema#string

J Bartek

http://www.w3.org/2001/XMLSchema#string

P2860

Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase

A human protein related to yeast Cdc6p

Cyclin-binding motifs are essential for the function of p21CIP1

Identification of G1 kinase activity for cdk6, a novel cyclin D partner

Cyclin A is required at two points in the human cell cycle

Cell cycle-regulated expression of mammalian CDC6 is dependent on E2F.

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells

Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

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396-410

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scholarly article

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10.1093/EMBOJ/18.2.396

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2

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18

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1999-01-15T00:00:00Z

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13400297

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9889196

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phosphorylation

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1171134

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