Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled
about
Identification of two novel activities of the Wnt signaling regulator Dickkopf 3 and characterization of its expression in the mouse retinaMouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expressionSyp1 is a conserved endocytic adaptor that contains domains involved in cargo selection and membrane tubulationWnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylationRegulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins.Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptorsWnt/β-catenin signaling in kidney injury and repair: a double-edged swordStructural Insight into the Mechanisms of Wnt Signaling Antagonism by DkkStructural Basis of Wnt Signaling Inhibition by Dickkopf Binding to LRP5/6Analysis of combinatorial effects of Wnts and Frizzleds on beta-catenin/armadillo stabilization and Dishevelled phosphorylationbeta-catenin destruction complex: insights and questions from a structural perspectiveWnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-cateninWnt signaling in the murine diastemaLRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-cateninWnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation.Engineering potent long-acting variants of the Wnt inhibitor DKK2Characterization of function of three domains in dishevelled-1: DEP domain is responsible for membrane translocation of dishevelled-1.Ixodes scapularis salivary gland protein P11 facilitates migration of Anaplasma phagocytophilum from the tick gut to salivary glandsUpdate on Wnt signaling in bone cell biology and bone disease.Chemical and genetic evidence for the involvement of Wnt antagonist Dickkopf2 in regulation of glucose metabolism.Wnt signalling pathway: a new target for the treatment of osteoporosis.Zebrafish Dkk3a protein regulates the activity of myf5 promoter through interaction with membrane receptor integrin α6bNuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interactionSecreted and transmembrane wnt inhibitors and activators.Increased liver carcinogenesis and enrichment of stem cell properties in livers of Dickkopf 2 (Dkk2) deleted mice.Canonical WNT signalling controls hair follicle spacing.RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.Microenvironmental targeting of Wnt/beta-catenin signals for hematopoietic stem cell regulation.Wnt pathway antagonists and angiogenesis.Wnt/Ca2+ signaling pathway: a brief overview.The Wnt pathway and the roles for its antagonists, DKKS, in angiogenesis.Low-density lipoprotein receptor-related protein 6 is a novel coreceptor of protease-activated receptor-2 in the dynamics of cancer-associated β-catenin stabilization.Dickkopf-3 regulates prostate epithelial cell acinar morphogenesis and prostate cancer cell invasion by limiting TGF-β-dependent activation of matrix metalloproteases.WNT signalling events near the cell membrane and their pharmacological targeting for the treatment of cancer.Epigenetic silencing of DKK2 and Wnt signal pathway components in human ovarian carcinoma.Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.Signaling crosstalk between TGFβ and Dishevelled/Par1b.The posterior HOXD locus: Its contribution to phenotype and malignancy of Ewing sarcoma.Stability elements in the LRP6 cytoplasmic tail confer efficient signalling upon DIX-dependent polymerization.Protease-activated receptor-1 (PAR1) acts via a novel Galpha13-dishevelled axis to stabilize beta-catenin levels.
P2860
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P2860
Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
Second cysteine-rich domain of ...... 6 independently of dishevelled
@ast
Second cysteine-rich domain of ...... 6 independently of dishevelled
@en
Second cysteine-rich domain of ...... 6 independently of dishevelled
@en-gb
Second cysteine-rich domain of ...... 6 independently of dishevelled
@nl
type
label
Second cysteine-rich domain of ...... 6 independently of dishevelled
@ast
Second cysteine-rich domain of ...... 6 independently of dishevelled
@en
Second cysteine-rich domain of ...... 6 independently of dishevelled
@en-gb
Second cysteine-rich domain of ...... 6 independently of dishevelled
@nl
prefLabel
Second cysteine-rich domain of ...... 6 independently of dishevelled
@ast
Second cysteine-rich domain of ...... 6 independently of dishevelled
@en
Second cysteine-rich domain of ...... 6 independently of dishevelled
@en-gb
Second cysteine-rich domain of ...... 6 independently of dishevelled
@nl
P2093
P2860
P921
P3181
P356
P1476
Second cysteine-rich domain of ...... 6 independently of dishevelled
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.M111131200
P407
P577
2002-02-22T00:00:00Z