Spartan/C1orf124 is important to prevent UV-induced mutagenesis
about
DVC1 (C1orf124) recruits the p97 protein segregase to sites of DNA damagePRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitryEukaryotic DNA polymerase ζA widely employed germ cell marker is an ancient disordered protein with reproductive functions in diverse eukaryotesDNA-dependent protease activity of human Spartan facilitates replication of DNA-protein crosslink-containing DNA.Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis.SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination.Spartan deficiency causes genomic instability and progeroid phenotypes.Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid featuresRelevance of simultaneous mono-ubiquitinations of multiple units of PCNA homo-trimers in DNA damage tolerance.Bub1 in Complex with LANA Recruits PCNA To Regulate Kaposi's Sarcoma-Associated Herpesvirus Latent Replication and DNA Translesion Synthesis.A non-catalytic role of DNA polymerase η in recruiting Rad18 and promoting PCNA monoubiquitination at stalled replication forksRole of p97/VCP (Cdc48) in genome stability.DNA damage tolerance: a double-edged sword guarding the genomeMechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN.Mechanisms of Post-Replication DNA RepairQuantitative microscopy uncovers ploidy changes during mitosis in live Drosophila embryos and their effect on nuclear size.Readers of PCNA modificationsThe identification of translesion DNA synthesis regulators: Inhibitors in the spotlight.Regulation of Rad6/Rad18 Activity During DNA Damage Tolerance.Strategic role of the ubiquitin-dependent segregase p97 (VCP or Cdc48) in DNA replication.Maintenance of Genome Integrity: How Mammalian Cells Orchestrate Genome Duplication by Coordinating Replicative and Specialized DNA Polymerases.Regulation of error-prone translesion synthesis by Spartan/C1orf124.Mechanisms of DNA-protein crosslink repair.SPRTN is a mammalian DNA-binding metalloprotease that resolves DNA-protein crosslinks.In vitro FANCD2 monoubiquitination by HHR6 and hRad18.Formation and repair of DNA-protein crosslink damage.Maternal Haploid, a Metalloprotease Enriched at the Largest Satellite Repeat and Essential for Genome Integrity in Drosophila Embryos.DNA protein crosslink proteolysis repair: From yeast to premature ageing and cancer in humans
P2860
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P2860
Spartan/C1orf124 is important to prevent UV-induced mutagenesis
description
2012 nî lūn-bûn
@nan
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Spartan/C1orf124 is important to prevent UV-induced mutagenesis
@ast
Spartan/C1orf124 is important to prevent UV-induced mutagenesis
@en
Spartan/C1orf124 is important to prevent UV-induced mutagenesis
@en-gb
Spartan/C1orf124 is important to prevent UV-induced mutagenesis
@nl
type
label
Spartan/C1orf124 is important to prevent UV-induced mutagenesis
@ast
Spartan/C1orf124 is important to prevent UV-induced mutagenesis
@en
Spartan/C1orf124 is important to prevent UV-induced mutagenesis
@en-gb
Spartan/C1orf124 is important to prevent UV-induced mutagenesis
@nl
prefLabel
Spartan/C1orf124 is important to prevent UV-induced mutagenesis
@ast
Spartan/C1orf124 is important to prevent UV-induced mutagenesis
@en
Spartan/C1orf124 is important to prevent UV-induced mutagenesis
@en-gb
Spartan/C1orf124 is important to prevent UV-induced mutagenesis
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Spartan/C1orf124 is important to prevent UV-induced mutagenesis
@en
P2093
Myoung Shin Kim
Yuichi J Machida
Yuka Machida
P2860
P304
P3181
P356
10.4161/CC.21694
P407
P577
2012-09-15T00:00:00Z